Transient Ischemic Dilatation Ratio in Stress Myocardial Perfusion SPECT in Diabetic Patients-A Systematic Review and Meta-Analysis

  • سال انتشار: 1392
  • محل انتشار: مجله دیابت و چاقی ایران، دوره: 5، شماره: 3
  • کد COI اختصاصی: JR_IJDO-5-3_007
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 65
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نویسندگان

Vahid Dolat-Abadi Farahani

MD, Assistant of cardiology, Department of Cardiology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Seid Kazem Razavi-ratki

MD, Nuclear Medicine Specialist, Department of Nuclear Medicine, Shahid Sadooghi University of Medical Sciences, Yazd, Iran

Nasim Namiranian

MD, Community Medicine Specialist, Yazd diabetes research center, Shahid Sadooghi University of Medical Sciences, Yazd, Iran

Mahmood Emami-Meybodi

MD, Assistant Professor of Cardiology, Department of Cardiology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Hossein Nough

MD, Assistant Professor of Cardiology, Department of Cardiology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Hossein Razavi

Assistant Professor of Oral and Maxillofacial Radiology, Faculty of Dentistry, Rafsanjan University of Medical Sciences . Rafsanjan , Iran

Naser Hossein Sartipzadeh

MD, Assistant Professor of Cardiology, Department of Cardiology, Afshar Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

چکیده

Abstract Objective: Abnormal values of the transient ischemic dilation (TID) ratio are associated with severe and extensive coronary artery disease (CAD). TID can be used as a diagnostic and prognostic marker of CAD in diabetic patients. The aim of current study was to determine the pooled estimate of TID ratio in single myocardial perfusion scan in diabetic patients by a systematic review and meta-analysis. Materials and Methods: The electronic databases of PubMed/MEDLINE, Scopus (EMBASE), Web of Science, and Cochrane Library up to December ۳۰, ۲۰۱۳ were searched. The reference lists of all included studies were searched for further studies. The search strategy was according to PICO characteristics. The heterogeneity between the studies was accounted with P< ۰.۱. The random/fixed effect model was used according to the heterogeneity. Point estimates were pooled estimate of TID ratio with ۹۵% confidence interval (CI) by pooling available data. Egger’s test was used to assess publication bias. Results: The primary search contained ۴۲۳ studies. Totally, ۱۷ studies met the inclusion criteria and the critical appraisal scores. The TID ratio in four single pharmacological stress studies with angiographic evidence of low risk or normal coronary artery disease was ۱.۰۷۹ (۹۵% CI: ۱.۰۷-۱.۰۸۹). Conclusion: Our findings were achieved according to the purpose of the study and the pooled estimate of TID±SD was calculated. The pooled estimate of TID was so smaller than the TID calculated in individual studies and so precise.

کلیدواژه ها

Transient ischemic dilatation, Single myocardial perfusion scan, Diabetes, Systematic review, Meta-analysis

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