The Effect of Combined Exercises and Consumption of Mulberry Leaf Extract on Serum Inflammatory Markers Level in Elderly Type ۲ Diabetes Mellitus Men
- سال انتشار: 1402
- محل انتشار: مجله دیابت و چاقی ایران، دوره: 15، شماره: 3
- کد COI اختصاصی: JR_IJDO-15-3_001
- زبان مقاله: انگلیسی
- تعداد مشاهده: 261
نویسندگان
Ph.D. Students in Sports Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
Associate Professor of Sports Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
Associate Professor, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran.
Associate Professor of Sports Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
Assistant Professor, Department of Pediatrics, School of Medicine Bu'ali Hospital, Ardabil University of Medical Sciences, Ardabil, Iran.
Associate Professor, Faculty of sport Sciences, Balikesir University, Balikesir, Turkey
چکیده
Objective: This study aimed to investigate the effect of ۸ weeks combined exercise and consumption of Mulberry leaf extract on the serum levels of inflammatory and atherosclerosis indicators in elderly men with type ۲ diabetes mellitus (T۲DM). Materials and Methods: ۴۰ elderly men T۲DM aged between ۶۵ to ۷۰ years old were purposefully selected and randomly divided into five equal groups (training, supplement, training+ supplement, placebo, and control). A daily dose of ۱۰۰۰ mg Mulberry leaf extract, ۳ times a day, was used for ۲ months by the supplement group. Training groups performed combined exercises for eight weeks, each week three sessions of ۹۰ minutes. Results: The results showed that the amount of salusin-β and interleukin-۶ in the training, training + supplement and supplement groups decreased significantly at the end of the study; Meanwhile, the level of salusin-α increased significantly in the training (P= ۰.۰۰۱), training + supplement (P= ۰.۰۰۱) and supplement (P= ۰.۰۱) groups. Also, the results of the covariance analysis showed that the amount of salusin-β and interleukin ۶ were lower (P= ۰.۰۰۱), and the level of salusin-α was higher significantly in the training (P= ۰.۰۰۱), training +supplement (P= ۰.۰۰۱), and supplement (P= ۰.۰۰۱) groups compared to the control groups. Conclusion: It seems that the consumption of Mulberry leaf extract, and combined exercises, is effective in controlling the inflammatory indicators and atherosclerosis related to diabetes in the T۲DM elderly. Corresponding Author: Roghayyeh Afroundeh View Orcid in Profile You can search for this author in PubMed Google Scholar Profileکلیدواژه ها
Interleukin ۶, Salusin-α, Salusin-β, Diabetes, Elderlyاطلاعات بیشتر در مورد COI
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