A review of the use of probiotics in the treatment of ulcerative colitis

سال انتشار: 1401
محل انتشار: دوفصلنامه آزمایشگاه پزشکی مدرن، دوره: 6، شماره: 1
کد COI اختصاصی: JR_MML-6-1_002
زبان مقاله: انگلیسی
تعداد مشاهده: 66

نویسندگان

Applied Virology Research Center, Baqiyatallah University of Medical Science, Tehran, Iran

چکیده

Ulcerative colitis (UC) is a chronic inflammatory disease that affects the colon and rectum. There is a constant need for improvements to be made in the current medical therapy since UC is extremely burdensome and kills many individuals. There are significant proportion of patients who experience adverse effects with current therapies. Consequently, new alternatives for the treatment of UC are constantly being sought. Probiotics are living microorganisms that are meant to improve one's health whether taken orally or topically. Gut microbiota balance, gut barrier function, and host immune responses all benefit from probiotic microorganisms. Probiotic supplementation is therefore becoming an increasingly popular treatment approach for treating UC and reducing chronic inflammation while also enhancing patients' quality of life. In order to assess the clinical effectiveness of probiotics, we examined the databases of PubMed, Web of Science, Embase, Science Direct, and Google Scholar. Probiotics are equally beneficial as conventional medication therapy in treating UC, according to several studies. Here, we've outlined the key findings of research that employed probiotics either alone or in conjunction with traditional UC treatment on individuals with UC.

کلیدواژه ها

۵-Aminosalicylates, Bifidobacterium, Gut microbiota, Lactobacillus, Probiotics, Ulcerative colitis

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