Investigating Risk Factors and Seroprevalence of Toxoplasma Gondii Antibodies in Patients Referred to the Central Laboratory of Ilam City, Iran

  • سال انتشار: 1402
  • محل انتشار: مجله بین المللی آزمایشگاه پزشکی، دوره: 10، شماره: 3
  • کد COI اختصاصی: JR_JIML-10-3_006
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 206
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نویسندگان

صغرا ویسی

Department of parasitology, Faculty of Paramedicine, Ilam University of Medical Sciences, Ilam, Iran

امین جایدری

Department of Pathobiology, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran

جهانگیر عبدی

Department of Parasitology, Faculty of Paramedicine, Ilam University of Medical Sciences, Ilam, Iran

ایمان پولادی

Department of Parasitology, Faculty of Paramedicine, Ilam University of Medical Sciences, Ilam, Iran

چکیده

Background and Aims: Toxoplasmosis is a protozoan infection caused by a forced intracellular parasite called Toxoplasma gondii, a branch of the apicomplexa found in humans and numerous species of animals. This study aimed to determine the titer of anti-Toxoplasma antibodies in patients referred to the Central Laboratory of Ilam City and to define their effective factors in the prevalence of this disease using the enzyme-linked immunosorbent assay (ELISA) method. Materials and Methods: The current study was a descriptive cross-sectional study with a random sampling of ۱۱۶ patients' serum referred to the Central Laboratory of Ilam City. Samples were analyzed using ELISA for the presence of Immunoglobulin (Ig)M, IgG antibodies against Toxoplasma gondii. Results: Twenty-three samples (۱۹.۸%) out of ۱۱۶ serum samples were detected using anti-Toxoplasma antibodies. Nineteen samples out of these ۲۳ (۱۶.۴%) samples were antibody IgG while the other ۴ were IgM antibodies. The results of the Chi-square test showed a significant difference between IgG-positive titer and sex, level of education, place of residence, age, and marital status; however, no significant difference was found between these variables and positive IgM titer. Conclusion: As a large number of people are susceptible to acute toxoplasmosis infection and lack proper health information, it is necessary to adopt monitoring and control measures by health care officials to prevent the infection through the necessary training and health recommendations.

کلیدواژه ها

ELISA, Risk factors, Seroepidemiologic studies, Toxoplasma gondii

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