The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity
- سال انتشار: 1402
- محل انتشار: نشریه بین المللی علوم تغذیه، دوره: 8، شماره: 3
- کد COI اختصاصی: JR_IJNS-8-3_002
- زبان مقاله: انگلیسی
- تعداد مشاهده: 251
نویسندگان
Department of Obstetrics and Gynecology, School of Medicine, Shahid Beheshti University Of Medical Sciences, Tehran, Iran
Laparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Laparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Laparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Iranian Hospital Dubai, Iranian Red Crescent Society, Dubai, United Arab Emirates
Department of surgery, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Laparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Laparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Laparoscopy Research Center, Shiraz University of medical sciences, Shiraz, Iran
چکیده
Background: Obesity is associated with developing polycystic ovary syndrome (PCOS). The present study investigated whether weight loss after bariatric surgery could improve symptoms and related hormones in women with morbid obesity.Methods: In a retrospective observational study, ۵۰ women aged ۱۸-۴۰ years with body mass index (BMI)=۴۲.۳ kg/m۲ who underwent laparoscopic Roux-en-Y gastric bypass (RYGB) were enrolled. Evaluation of anthropometric data, serum testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), fasting plasmaglucose (FPG), and lipid profile were measured preoperatively and at ۱-year follow-upResults: Of ۵۰ women, ۳۲ (۶۴%) women were diagnosed to have PCOS. The mean BMI at ۱-year follow-up was ۲۷.۰۵ kg/m۲. Hirsutism and irregular menstruation resolved entirely among ۶۸.۸% (۱۱/۱۶) and ۱۰۰% (۱۸/۱۸) at ۱-year follow-up. There was a significant decrease in total serum testosterone (۲.۱±۰.۲ to ۰.۹±۰.۱ ng/mL) and LH (۸.۵±۳.۳۶ to ۵.۰۲±۲.۴ mIU/mL) at ۱-year follow-up, whether changes in levels of serum FSH, PRL were not significant.Conclusion: Bariatric surgery was effective in weight loss and improvement of PCOS symptoms and related hormones in women with morbid obesity. Thus, women with PCOS and morbid obesity should be eligible for bariatric surgery.کلیدواژه ها
Polycystic ovary syndrome, Obesity, Bariatric surgery, Weight Loss, Iranاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.