The role of ultrasound in the prediction of GDM in early pregnancy

  • سال انتشار: 1402
  • محل انتشار: مجله دانشگاه علوم پزشکی کرمان، دوره: 30، شماره: 4
  • کد COI اختصاصی: JR_JKMU-30-4_001
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 211
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نویسندگان

Maryam Dalili

Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iranan University of Medical Sciences

shahrzad Moeinaddini

Department of Obstetrics and Gynecology, School of Medicine, Endocrinology and Metabolism Research Center of Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran Department of Obstetrics and Gynecology, School of Medicine,

hosein Gozashti

Department of Internal Medicine, School of Medicine, Endocrinology and Metabolism Research Center of Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iranan University of Medical Sciences

Mehdi Torabi

Department of Emergency Medicine, Afzalipour Faculty of Medicine, Kerman University of Medical Sciences, Kerman, Iran

Moghadameh Mirzaee

Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran

Afsaneh Mahdizadeh

Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran

چکیده

Background In order to detect the gestational diabetes mellitus (GDM) in pregnant women as soon as possible, the aim of this study was to investigate the role of ultrasound in predicting GDM at early pregnancy by measuring the thickness of abdominal subcutaneous adipose tissue.Methods and MaterialsThis was a longitudinal study performed on pregnant women at the weeks of ۱۱ to ۱۴ of pregnancy. All the women referred during this time were screened for the thickness of abdominal subcutaneous adipose tissue, which was measured by trans-abdominal ultrasound. The patients were followed up by performing the oral glucose tolerance test (OGTT) between the weeks of ۲۴-۲۸. Finally, abdominal subcutaneous adipose tissue thickness and other variables were compared between women with and without GDM. Oral consent was obtained from patients.Results۲۱۰ pregnant women were enrolled in the study. The mean of abdominal subcutaneous adipose tissue thickness was measured by ultrasound as ۱.۷۲ ± ۰.۳۳ mm. There was a statistically significant relationship between GDM and ultrasound-derived subcutaneous adipose tissue thickness (P < ۰.۰۰۰۱). At the cut-off point of ۲.۰۱, the sensitivity, specificity, and area under curve (AUC) values were ۹۱%, ۹۲%, and ۰.۹۶, respectively.ConclusionMeasuring the thickness of the abdominal subcutaneous adipose tissue at early pregnancy may be useful in predicting GDM in the second trimester of pregnancy. Maternal higher age and weight gain, increased parity, and positive family histories of diabetes, preeclampsia, hypertension, and recurrent abortion may also increase the risk of GDM.

کلیدواژه ها

Abdominal subcutaneous adipose tissue, Gestational diabetes mellitus, Pregnancy, Ultrasound

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