The correlation between helicobacter pylori infection and squamous cell carcinoma of larynx and hypopharynx
- سال انتشار: 1386
- محل انتشار: مجله علمی گوش و حلق و بینی ایران، دوره: 19، شماره: 48
- کد COI اختصاصی: JR_IJOTO-19-48_004
- زبان مقاله: انگلیسی
- تعداد مشاهده: 172
نویسندگان
Otolaryngologist, Mashhad University of Medical Sciences
Otolaryngologist, Mashhad University of Medical Sciences
Orthodontic assistant
Specialist in internal diseases and digestion
Internal medicine assistant
Otolaryngologist, Mashhad University of Medical Sciences
Statistics specialist
چکیده
ntroduction: From the most important laryngeal and hypopharyngeal cancer risk factors are smoking, alcohol and anemia. But reflux is one of the suggested etiologies. Pregnancy, Nonstroidal anti inflammation drugs and drugs decreasing the lower esophageal sphincter pressure will increase the reflux. Helicobacter pylories role in reflux formation is different due to the involved region and can also have a decreasing role and decline the rate of a series of esophageal and upper aero digestive system disease. Materials and Methods: This cross – sectional and case – control study was done in Qaem medical hospital, Mashhad during the years ۱۳۸۴ and ۱۳۸۵, for serum level detection of anti – H.pylori IgG and IgA antibodies in blood samples of both control and case groups. The variables were age, sex and serum test results. Results: ۴۵ patients (۳۹ male and ۶ female) and ۴۲ controls (۳۳ male and ۹ female) were evaluated. ۲ groups were matched for age and sex. Positive IgG and IgA results in patients in order was ۳ person (۶.۶ percent) and ۳ person (۶.۶ person) and in control group ۲۶ person (۶۱.۹%) and ۱۲ person (۲۸.۵%). Result (P> ۰.۰۰۱) was for healthy group showing the protective effect of H. Pylori against laryngeal cancer.Conclusion: In our study, control group with a meaningful difference was affected by H.Pylori infection. This can be due to a protective effect for H. Pylori against the laryngeal andIhypopharyngeal malignancies. Prospective studies and simultaneously evaluation of reflux, H. Pylori infection and the regain of gastric location are suggested.کلیدواژه ها
Helicobacter pylori, Squamous cell carcinoma, Larynx, Hypopharynxاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.