Skin Substitutes; A New Approach to Wound and Burn Treatment Based on Tissue Engineering

  • سال انتشار: 1401
  • محل انتشار: نهمین کنگره سالانه زخم و ترمیم بافت
  • کد COI اختصاصی: WTRMED09_048
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 114
دانلود فایل این مقاله

نویسندگان

Mohammad Hassan Yazdanfar

MSc Students, Bioceramics and Implants Laboratory, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran

Zahra Mohammadi

Lecturer, Bioceramics and Implants Laboratory, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran

Abdorreza Sheikh-Mehdi Mesgar

Lecturer, Bioceramics and Implants Laboratory, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran

Zahra Mohammadi

Lecturer, Bioceramics and Implants Laboratory, Faculty of New Sciences and Technologies, University of Tehran, Tehran, Iran

چکیده

Skin is the largest organ in the human body, and it has the function of protecting the body from exogenous substances and stand as a barrier to fluid loss and trauma. It also maintains the balance and protects the body from external factors such as bacteria, chemicals, and temperature. When the integrity of skin is compromised due to injury as in burns the coverage of skin has to be restored to facilitate repair and regeneration. Conventional wound care may sometimes lead to suboptimal wound healing and significant morbidity and mortality for patients. In cases like chronic wounds, including diabetic ulcers, pressure ulcers, venous ulcers, and arterial insufficiency ulcers, and second- or third-degree burns which are both difficult and expensive to treat, skin substitutes are preferred for wound coverage, not only because of mentioned benefits, but also because of their advantages in cosmetic issues and scar treatment. Recent advances in tissue engineering techniques, enabled developing new arising skin substitutes. The aim of this paper is to discuss and classify the different types of currently available commercial skin substitutes, and to mention their limitations, to gain a more precise and practical perspective, leading us to identify and meet the essential needs in this area.

کلیدواژه ها

Tissue Engineering - Wound Healing - Skin Substitutes - Chronic Wounds - Burns - Commercial Products

مقالات مرتبط جدید

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.