Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

  • سال انتشار: 1396
  • محل انتشار: فصلنامه میکروب شناسی پزشکی ایران، دوره: 11، شماره: 1
  • کد COI اختصاصی: JR_IJMM-11-1_001
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 88
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نویسندگان

Ahmad Tavakoli

Department of Virology, Faculty of medicine, Iran University of Medical Sciences, Tehran, Iran

Mohammad Hadi Karbalaie Niya

Department of Virology, Faculty of medicine, Iran University of Medical Sciences, Tehran, Iran

Mohsen Keshavarz

Department of Virology, Faculty of medicine, Iran University of Medical Sciences, Tehran, Iran

Fahimeh Safarnezhad Tameshke

Gastrointestinal & Liver Disease Research Center (GILDRC), Iran University of Medical Sciences, Tehran, Iran

Seyed Hamidreza Monavari

Department of Virology, Faculty of medicine, Iran University of Medical Sciences, Tehran, Iran

چکیده

The Middle East respiratory syndrome coronavirus (MERS-CoV) as a causative agent of severe lower respiratory tract infection in humans, considered as a global threat, especially against to Persian Gulf countries. Since its discovery in ۲۰۱۲, MERS-CoV has spread ۲۷ countries affecting about ۱۸۰۰ people and caused more than ۶۰۰ deaths in worldwide. In comparison to SARS (severe acute respiratory syndrome), MERS-CoV appears to have a higher mortality rate (۴۰% versus ۱۰%) and is particularly more severe in patients with underlying medical conditions. Until now, the most MERS-CoV cases (more than ۸۵ percent) have had a history of travel or residence in the Middle East countries. A possible intermediate host for MERS-CoV is camel. Clinical manifestations of MERS range from mild or asymptomatic disease to acute respiratory syndrome and multi-organ failure resulting in death, mostly in individuals with preexisting medical co-morbidities. There is no specific antiviral treatment for MERS and infection prevention and control practices are necessary to prevent spread of MERS-CoV in health care facilities. In present study, we have briefly outlined the recent information about the epidemiology, clinical features, diagnosis, treatment and prevention of MERS-CoV.

کلیدواژه ها

Middle East respiratory syndrome, MERS-CoV, Acute respiratory illness, SARS, کوروناویروس سندروم تنفسی خاورمیانه, کوروناویروس مرس, بیماری تنفسی حاد, سارس

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