Identification of Etiologic Agents of Actinomycetal Infections among Patients Referred to the Health Faculty of Tehran University of Medical Sciences
- سال انتشار: 1396
- محل انتشار: فصلنامه میکروب شناسی پزشکی ایران، دوره: 11، شماره: 6
- کد COI اختصاصی: JR_IJMM-11-6_007
- زبان مقاله: انگلیسی
- تعداد مشاهده: 170
نویسندگان
Department of Microbiology, Faculty of Basic Sciences, Islamic Azad University, Science and Research Branch, Tehran, Iran
Department of Medical Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Department of Tuberculosis and Pulmonary Research, Microbiology Research Center, Pasteur Institute of Iran, Tehran, Iran
چکیده
Background and Aims: Actinomycetes are a group of Gram-positive bacteria that have filamentous morphology with about one micron diameter. Actinomyces, Nocardia and Streptomyces are classified in this group. In this study, the etiological agents of actinomycetal infections were determined among patients referred to the Health faculty of Tehran University of Medical Sciences (TUMS). Materials and Methods: To determine the status of actinomycetes diseases, ۴۶۵ specimens including the broncho-alveolar lavage (BAL), cerebrospinal fluid (CSF), tissue biopsy, abscess discharge and other clinical materiasl were examined via microscopic observation and culture methods. (۲۰۱۱-۲۰۱۵) Results and Conclusions: Out of the ۴۶۵ specimens, ۲۰ (۴.۳%) were diagnosed as infected which included ۱۱(۵۵% ) Actinomyces and ۹ (۴۵% ) Nocardia. The most positive results were associated with pulmonary infections. Among the infected patients, ۶۰ % (۱۲) were male and ۴۰% (۸) were female. The results of this study showed that the prevalence of Actinomyces and Nocardia was similar, being more predominant among men compared to women. In order to obtain the appropriate results, it is recommended that samples are taken during doctor's visit and before starting a treatment. It is also recommended to use molecular methods such as PCR and RT-PCR for better identification and comparison with phenotypic methods.کلیدواژه ها
Actinomycosis, Nocardiosis, Actinomycetal, BAL, اکتینو مایکوزیس, نوکاردیوزیس, اکتینومایستال, BALاطلاعات بیشتر در مورد COI
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