Comparative Dosimetric Evaluation of Volumetric-Modulated Arc Therapy (VMAT) Versus Intensity-Modulated Radiotherapy (IMRT) in Thoracic Esophageal Cancer
- سال انتشار: 1402
- محل انتشار: مجله فیزیک پزشکی ایران، دوره: 20، شماره: 3
- کد COI اختصاصی: JR_IJMP-20-3_006
- زبان مقاله: انگلیسی
- تعداد مشاهده: 116
نویسندگان
Department of Physics, Tilak Dhari P. G. College, Jaunpur, (U.P.) - ۲۲۲۰۰۲, INDIA and Department of Radiation Oncology, Lecturer(Physicist), Uttar Pradesh University of Medical Sciences, Saifai etawah-UP ۲۰۶۱۳۰ India
Department of Physics, Tilak Dhari P. G. College, Jaunpur, (U.P.) - ۲۲۲۰۰۲, INDIA
Department of Radiation Oncology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah (U.P.) - ۲۰۶۱۳۰, INDIA
Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand Gomti Nagar, Lucknow -۲۲۶۰۱۰
Department of Physics, Tilak Dhari P. G. College, Jaunpur, (U.P.) - ۲۲۲۰۰۲, INDIA
Department of Radiation Oncology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Vibhuti Khand Gomti Nagar, Lucknow -۲۲۶۰۱۰ India
چکیده
Introduction: With the introduction of Intensity Modulated Radiotherapy (IMRT) approach, better dosimetry results and patient outcomes has been attained for various anatomical sites. In present study, a comparative dosimetric evaluation of Volumetric-Modulated Arc Therapy (VMAT) versus two techniques of IMRT i.e. Dynamic IMRT (d-IMRT) and step & shoot IMRT (ss-IMRT) was done for thoracic esophageal cancer.Material and Methods: VMAT, ss-IMRT, and d-IMRT plans were generated on the Computed Tomography Simulator data sets of ۱۳ Patients with thoracic esophageal carcinoma who had been treated earlier. The prescription dose for each patient was ۵۰.۴ Gy in ۲۸ fractions. All the plans were optimized to achieve greater or equal to ۹۵% of the prescribed dose to the Planning Target Volume (PTV). Dose to PTV and organ at risk (OAR) were compared with the help of Dose Volume Histogram (DVH).Results: VMAT and d-IMRT plans were nearly equivalent for PTV coverage, homogeneity index (HI), and uniformity index (UI) (p> ۰.۰۵). However, VMAT and d-IMRT plans had superior PTV coverage, HI, and UI, (p < ۰.۰۱) than ss-IMRT. For PTV, the Dmean, D۹۸, and D۹۵ values in ss-IMRT were significantly less than VMAT and d-IMRT (p< ۰.۰۵).Conclusion: All three techniques are able to provide a homogeneous and conformal dose distribution. VMAT offers better homogeneous dose distribution and may be preferred for treating thoracic esophageal carcinoma. Thus, the multi-arc VMAT technique may be a better option with equivalent or superior dose distribution, uniformity, and homogeneity.کلیدواژه ها
Radiotherapy, Dosimetry, Esophagus, Computed Tomography, Intensity Modulated, Radiotherapy planning, Homogeneity Index, conformity indexاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.