Tobacco smoke and increased risk of coronavirus transmission

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 68

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شناسه ملی سند علمی:

THMED04_138

تاریخ نمایه سازی: 19 اردیبهشت 1402

چکیده مقاله:

Background: Tobacco and hookah (water pipe) smoking is a global health problem and animportant risk factor for various diseases. Tobacco smoking increases the salivary flow, reducesthe pH level in the mouth, and changes the quality of the saliva. Genes affect virus infectivity,such as in COVID-۱۹, and immune response. Genes related to the angiotensin-converting enzymeare an example of such genes. High amounts of these genes are created in the oral epithelial cellsand respiratory tract in smokers versus non-smokers. We hypothesize that an increasedconcentration of coronavirus in the mouth of smokers elevates the risk of virus transmission.Method: In this retrospective cohort study, we examined all confirmed COVID-۱۹ patients whowere outpatients in ۲۰۲۱. We extracted their demographic information and tobacco and hookahsmoking history in the past months. They were divided into two groups: smokers and nonsmokers.The family members of these patients were followed up for ۲۸ days or until theoccurrence of symptoms. Then, the secondary attack rate (SAR) was calculated. SAR is aparameter to assess the magnitude of the risk, which represents the number of people infectedthrough the transmission from the index case.Results: This retrospective cohort study was conducted on ۱۴۷ patients with COVID-۱۹. Themean age of smokers and nonsmokers was respectively ۴۲.۹ ± ۱۳.۲ and ۴۳.۸ ± ۱۵.۵ years. In thecase group (smokers), ۱۳۰ family members were exposed to coronavirus and ۷۳ people wereinfected, which gives SAR=۵۶%. In the comparison group (nonsmokers), ۱۳۳ family memberswere exposed and ۵۰ were infected, resulting in SAR=۳۷.۵%.Conclusion: Tobacco and hookah smoking can lead to an elevated rate of virus transmission andsecondary attack rate.

کلیدواژه ها:

Secondary Attack Rate (SAR) ، Transmission ، Smoker ، Nonsmoker ، COVID-۱۹ ، Tobacco And Hookah Smoking

نویسندگان

Mahboubeh Neamatshahi

Sabzevar University of Medical Sciences, Sabzevar, Iran.

Bita Barghamadi

Sabzevar University of Medical Sciences, Sabzevar, Iran.

Aghil Keykhosravi

Sabzevar University of Medical Sciences, Sabzevar, Iran.

Akram Foshtanghi

Sabzevar University of Medical Sciences, Sabzevar, Iran.