Predictors of Mortality in Sepsis Patients Resulting from Severe and Critical COVID-۱۹
- سال انتشار: 1402
- محل انتشار: مجله علوم دارویی و شیمی، دوره: 6، شماره: 9
- کد COI اختصاصی: JR_JMCH-6-9_010
- زبان مقاله: انگلیسی
- تعداد مشاهده: 232
نویسندگان
Division of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang, Indonesia
Department of Internal medicine, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang Indonesia
Department of Microbiology, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang Indonesia
Division of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang, Indonesia
Division of Tropical Medicine and Infectious Diseases, Department of Internal Medicine, Faculty of Medicine, Diponegoro University, Dr. Kariadi Hospital, Semarang, Indonesia
چکیده
Patients with severe and critical COVID-۱۹ may exhibit sepsis and mortality resulting from multi-organ failure. Neutrophil-lymphocyte-ratio (NLR) values, C-reactive protein (CRP) levels, sequential organ failure assessment (SOFA), and acute physiology and chronic health evaluation II (APACHE-II) scores were used to assess the risk of mortality in sepsis patients resulting from severe COVID-۱۹ infection. The adequacy of NLR, CRP, SOFA, and APACHE-II scores were evaluated as predictors of mortality in septic COVID-۱۹ patients at Dr. Kariadi Hospital Semarang, Indonesia, between August ۲۰۲۱ and July ۲۰۲۲. The subjects included severe and critical COVID-۱۹ patients who fulfilled the WHO interim guidelines and Sepsis-۳ criteria. A total of ۲۱۱ patients were included, which were divided into survivor (n = ۱۱۶) and non-survivor (n = ۹۵) groups. NLR values, CRP levels, SOFA, and APACHE-II scores were measured within ۲۴ hours of patient admission. Univariate and multivariate logistic regression analyses were used to identify the risk factors for COVID-۱۹ mortality. Receiver operating characteristic curve analysis was used to predict the mortality of severe COVID-۱۹ patients. The results indicated that the APACHE-II score was an independent predictor of mortality in sepsis patients resulting from severe and critical COVID-۱۹.کلیدواژه ها
Neutrophil, Lymphocyte, ratio (NLR) C, reactive protein (CRP) SOFA score APACHE, II score Mortality COVID, ۱۹اطلاعات بیشتر در مورد COI
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