Curcumin’s effect on serum zinc, copper and magnesium levels in obese individuals

  • سال انتشار: 1402
  • محل انتشار: مجله گیاهان دارویی ابن سینا، دوره: 13، شماره: 3
  • کد COI اختصاصی: JR_AJP-13-3_001
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 269
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نویسندگان

Maryam Saberi-Karimian

Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

Arezoo Orooji

Student Research Committee, Department of Epidemiology and Biostatistics, Faculty of Health, Mashhad University of Medical Sciences, Mashhad, Iran

Niloofar Taghizadeh

International UNESCO center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran

Mansoureh Sadat Ekhteraee Toosi

International UNESCO center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran

Gordon A. Ferns

Brighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN۱ ۹PH, UK

Malihe Aghasizadeh

Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Majid Ghayour-Mobarhan

International UNESCO center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran

چکیده

Objective: The obesity prevalence is growing worldwide. There is strong evidence indicating that a disturbance of zinc, copper and magnesium concentrations is associated with the development of obesity and its related diseases. Our aim was to determine the effect of curcumin supplementation on serum zinc, magnesium and copper in obese individuals.Materials and Methods: In this randomized crossover trial study, thirty obese patients with an age range of ۱۸ to ۶۵ years were randomized to treatment with curcumin ۱ g/day or placebo for ۳۰ days. There was then a two-week wash-out period, after which, subjects crossed to the alternate regimen. Serum levels of zinc, copper and magnesium were determined at baseline and at the end of the study.Results: The study groups were similar to each other in base line characteristics. We did not observe significant impacts (p> ۰.۰۵) of curcumin on Cu, Zn, Mg serum concentrations.Conclusion: Curcumin administration at a dose of ۱ g/day for ۳۰ days did not affect serum Cu, Zn, Mg levels in obese subjects.

کلیدواژه ها

Obesity, Curcumin, zinc, Copper, magnesium

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