Effect of mineral nanoparticles obtained from thermal spring water on COVID-۱۹
- سال انتشار: 1401
- محل انتشار: مجله مدیریت و مهندسی بهداشت محیط، دوره: 10، شماره: 1
- کد COI اختصاصی: JR_EHEM-10-1_004
- زبان مقاله: انگلیسی
- تعداد مشاهده: 130
نویسندگان
Corresponding author: Department of Materials Science and Engineering, Shahid Bahonar University of Kerman, Kerman, Iran
Department of Materials Science and Engineering, Shahid Bahonar University of Kerman, Kerman, Iran
Department of Medical Laboratory Science, School of Paramedical, Kermanshah University of Medical Sciences, Kermanshah, Iran
Department of Materials Science and Engineering, Shahid Bahonar University of Kerman, Kerman, Iran
چکیده
Background: Coronavirus disease ۲۰۱۹ (COVID-۱۹) is presently a life-threatening condition, and despite of multiple attempts, no functional method has been introduced against this pandemic problem yet. In this study, for the first time, the possible antiviral aspects of mineral nanoparticles (MNPs) obtained from a natural source, thermal spring water, were evaluated. Methods: At first, MNPs obtained from the Gishki thermal spring, Kerman province, Iran, were characterized by transmission electron microscope (TEM). Then, the presence of mineral elements in MNPs was identified by X-ray fluorescence (XRF), Energy-dispersive X-ray spectroscopy (EDX), inductively coupled plasma mass spectrometry (ICP-MS), and MTT assay. Finally, ۱۷ cases suspected of COVID-۱۹ were randomly selected, and their nasal swab samples were exposed to two concentrations of MNPs (۵۰ and ۱۰۰ u/mL). Results: The results of real-time polymerase chain reaction (RT-PCR) test manifested that MNPs had a destructive effect on ۴ (۳۳%) COVID-۱۹ cases. Conclusion: Therefore, MNPs of thermal spring water may act as an obstacle against COVID-۱۹.کلیدواژه ها
Hot springs, COVID-۱۹, Minerals, Antiviral agents, X-Raysاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.