Amir Aria - Department of Internal Medicine, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
Mahnaz Momenzadeh - Department of Clinical Pharmacy and Pharmacy Practice, Isfahan University of Medical Sciences, Isfahan, Iran
Keyvan Ghadimi - Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
Mozhgan Mortazavi - Department of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

مقدمه : In the worldwide, there are the pandemic of the virus coronavirus disease ۲۰۱۹ (COVID-۱۹) and there is no approved treatment for this disease. هدف : In Covid-۱۹ patients neurological symptoms could be more severe, while in the case mentioned in this study, the patient had no evidence of respira tory infection.معرفی بیمار : This study reported a new case with COVID ۱۹ with neurological symptoms such as headache and loss of consciousness without any symptoms and imaging of COVID ۱۹ in admission but RT-PCR COVID-۱۹ of patient was positive and during hospitalization patient had increas ing cerebrospinal fluid (CSF) volume in sub-arachnoid space, micro-hemorrhaging in basal ganglia and down ward cerebellar tonsile herniation in the brain imaging, also there were rhabdomyolysis and thrombotic thrombocytopenic purpura in the lab data. Finally, based on abnormal electroencephalogram (EEG), brain death was diagnosed for pa tient in end of hospitalization. In the ۸th of admission day, the patients died after cardiovascular arrest. بحث و نتیجه گیری: Neurological symptoms could be more severe, while in the case mentioned in this study, the patient had no evidence of respira tory infection.Our study reported that COVID ۱۹ infection could be complicate neurological disorders such as brain death or CVA without respiratory compli cation, in this regarding COVID ۱۹ is a novel disease with relatively high mortality rate and also this disease could be present with differ ent complication and disorders.

COVID ۱۹, rhabdomyolysis, brain death, headache