Investigation of the Nonlinear Refractive Index of MCF۷ and MCF۱۰A Breast Cell Lines for Optical Diagnosis

  • سال انتشار: 1401
  • محل انتشار: مجله بین المللی بیوفوتونیک و مهندسی پزشکی، دوره: 2، شماره: 1
  • کد COI اختصاصی: JR_JIBBO-2-1_005
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 315
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نویسندگان

Bahareh Khaksar Jalali

۱. Department of physics, Kharazmi University, Tehran, Iran. ۲. Laser and Biophotonics in Biotechnologies Research Center, Islamic Azad University of Isfahan (Khorasgan) branch, Isfahan, Iran.

Somayeh Salmani Shik

۱. Department of physics, Kharazmi University, Tehran, Iran. ۲. Applied Sciences Research Center, Kharazmi University, Karaj, Iran.

Latifeh Karimzadeh Bardee

Department of animal biology, Faculty of biological sciences, kharazmi university, Tehran, Iran.

sharifeh shahi

۱. Department of Biomedical Engineering, Islamic Azad University of Isfahan (Khorasgan) branch, Isfahan, Iran. ۲. Laser and Biophotonics in Biotechnologies Research Center, Islamic Azad University of Isfahan (Khorasgan) branch, Isfahan, Iran.

چکیده

To demonstrate that the Z-scan technique is a reliable approach for diagnosing normal and cancer cells, the absorption coefficient (α), nonlinear refractive index (n۲) of normal (MCF۱۰A) and cancer cell lines (MCF۷) were examined. According to our findings of the optical properties of cells, cancer cells shown to have higher linear absorption coefficient than normal cells as well as nonlinear refractive index (n۲) of different signs but the same order of (۱۰-۷ cm۲/W). This method is a quick method for differentiating between normal and cancerous breast cells, making it suitable for use in clinical stages in the future. This is because of the obvious fundamental difference between the optical behavior of normal and cancer cells, as well as the affordability, the potential for reproducibility without compromising sample quality, and the high accuracy.

کلیدواژه ها

Cancer Diagnosis, Linear Absorption, MCF۷, MCF۱۰A, Optical Coefficients, Z-scan technique

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