Prevalence of MRSA Bacteremia in Liver Transplant Patients: A Systematic Review and Meta-Analysis
- سال انتشار: 1401
- محل انتشار: فصلنامه عفونت، اپیدمیولوژی و پزشکی، دوره: 8، شماره: 3
- کد COI اختصاصی: JR_IEM-8-3_010
- زبان مقاله: انگلیسی
- تعداد مشاهده: 147
نویسندگان
Microbiology Department, Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Biostatistics, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Shiraz University of Medical Sciences
Microbiology Department, Burn and Wound Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
چکیده
Backgrounds: Infection is one of the major threats to liver transplant patients and significantly affects associated mortality and morbidity. Serious infections are likely to occur a few months after transplantation, and most of them are bacterial. The aim of this study was to evaluate the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia in liver transplant patients. Materials & Methods: In this systematic review and meta-analysis, Preferred Reporting Items for systematic reviews and meta-analysis guidelines were used. International databases including PubMed, Scopus, Web of Sciences, Embase, and Cochrane were searched by related MeSH terms and keywords for studies published until July ۲۶, ۲۰۲۰. The current study was registered by a pre-defined protocol in PROSPRO. Findings: After a comprehensive literature search, ۱۱ articles were selected for inclusion in the analysis. The prevalence of MRSA in liver transplant patients was ۷۵% (۹۵% CI: ۵۸% - ۸۹%); however, an evident heterogeneity was observed between the studies (I۲= ۸۷.۸۴%, p< .۰۰۱). Conclusion: In conclusion, this study results demonstrate that the prevalence of post-transplant MRSA colonization bacteremia is high among liver transplant patients. This should be considered seriously, and efforts should be made to prevent mortality in this group of patients.کلیدواژه ها
MRSA, Bacteremia, Liver transplant, Meta-analysisاطلاعات بیشتر در مورد COI
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