High Intensity Interval Training and EndothelialFunction in Women with Polycys tic Ovary Syndrome

Background: Polycys tic ovary syndrome (PCOS) is one of themos t common endocrine disorders in women of reproductiveage. Given that PCOS is associated with an increased cardiovasculardisease (CVD) risk, and reduced endothelial functioningincreases this risk, the clinical importance of lifes tyleimprovement on endothelial function in PCOS needs inves tigation.The main purpose of this s tudy was to evaluate the effectof ۸ weeks high intensity interval training (HIIT) on serum levelsof VCAM-۱, and E-selectins in women with PCOS.Materials and Methods: Thirty females with PCOS aged between۱۸ and ۴۰ years were randomly categorized to an ۸-weekhigh intensity interval training intervention (HIIT), or a controlgroup. The HIIT program include ۸ weekly sessions (۳ sessionsa week). After an overnight fas t of ۱۰ hours, fas ting serum sampleswere collected before and after intervention. S tatis ticalanalysis was performed using SPSS software (version ۲۳). Pless than ۰.۰۵ was considered s tatis tically significant.Results: After ۸-week intervention a significant reduction inserum E-selectin levels was observed in HIIT group, but not incontrol group. Regarding sVCAM۱, no significant changes wasobserved before and after intervention in both groups.Conclusion: These findings demons trated that ۸ weeks HIIT inPCOS patients could be prescribed to improve endothelial function

کلیدواژه ها:

Endothelial Function ، Exercise ، High Intensity IntervalTraining Intervention ، Polycys tic Ovary Syndrome