Synergistic combinations of metal, metal oxide, or metalloid nanoparticles plus antibiotics against resistant and non-resistant bacteria

سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 148

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شناسه ملی سند علمی:

JR_MNBA-1-1_001

تاریخ نمایه سازی: 14 دی 1401

چکیده مقاله:

The emergence of drug resistance in pathogenic bacteria due to the indiscriminate use of antibiotics is a major challenge to global public health. Therefore, improved and more effective antibacterial agents are urgently needed as alternatives to conventional antibiotics. Nanotechnology-based approaches can take advantage of the nano–bacteria interface to improve microbial killing both in vitro in and in vivo. In this way, modified metal or metal oxide nanoparticles combined with antibiotics could be a novel class of antibacterial agents with synergistic effects against antibiotic-resistant bacteria. This review discusses recent advances in the synthesis and functionalization of these nanomaterials, and considers their advantages and disadvantages.

نویسندگان

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Nanobiotechnology Department, Faculty of Innovative Science and Technology, Razi University, Kermanshah, Iran; Department of Biological Sciences, Faculty of Science, University of Kurdistan, Sanandaj, Kurdistan, Iran

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Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, ۲۰۲۸, South Africa Wellman Centre for Photomedicine, Massachusetts General Hospital, Boston, MA ۰۲۱۱۴, USA Department of Dermatology, Harvard

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Department of Pharmacy, Faculty of Sciences, Universidad Nacional de Colombia, South America, Colombia

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Chembiotech Laboratories, Advanced Science and Technology Institute, Tenbury Wells, WR۱۵ ۸FF, UK

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Department of Pharmacy, Abdul Wali Khan University Mardan, Khyber-Pakhtunkhwa, Pakistan