Comparison of the effect of licorice vaginal cream and estrogen vaginal cream on sexual function of postmenopausal women: An RCT

  • سال انتشار: 1401
  • محل انتشار: مجله طب تولید مثل ایران، دوره: 20، شماره: 11
  • کد COI اختصاصی: JR_IJRM-20-11_007
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 212
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نویسندگان

Parisa Ahmadizad

Department of Nursing, School of Nursing and Midwifery, Student Research Committee, Ilam University of Medical Sciences, Ilam, Iran.

Masoumeh Shohani

Department of Nursing, School of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran.

Ashraf Direkvand Moghadam

Department of Midwifery, School of Nursing and Midwifery, Ilam University of Medical Sciences, Ilam, Iran.

Anahita Jalilian

Department of Obstetrics and Gynecology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

Hojat Sayadi

Department of Biostatistics, School of Health, Non-Communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran.

Naser Abbasi

Department of Pharmacology, School of Medicine, Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran.

چکیده

Background: Menopause is a stage in woman’s life that some women experience in middle age and some at a younger age (premature menopause). Low levels of ovarian hormones, during menopause can lead to various complications. Menopause is one of the factors that can affect a woman's sexual function. Objective: The present study was conducted to compare the effect of licorice vaginal cream and estrogen vaginal cream on the sexual function of postmenopausal women. Materials and Methods: In this randomized clinical trial study, ۸۲ postmenopausal women who were referred to health centers in Ilam, Iran from July to November ۲۰۲۰ were randomly divided into ۲ groups (n = ۴۱/each). One group was given estrogen vaginal cream ۲%, and the other vaginal licorice cream ۲%. Participants used the ۲ medications for ۱۴-day periods each. We used the finite randomization method. Data collection questionnaires, including a demographic information questionnaire before treatment and a female sexual function index questionnaire were completed before, one month after the medication, and ۲ months after using the medication. Results: The mean score of sexual function in the licorice group was ۱۷.۸۶ ± ۴.۳۷ and increased to ۲۰.۳۱ ± ۴.۶۳ at the end of the study. The mean score of sexual function in the estrogen group was ۱۷.۱۴ ± ۳.۹۹ and increased to ۲۲.۹۷ ± ۵.۰۹ at the end of study (p = ۰.۰۱۵). Conclusion: The effect of estrogen vaginal cream on the sexual function of postmenopausal women was greater than licorice vaginal cream.

کلیدواژه ها

Vagina, Post menopause, Glycyrrhiza, Estrogens., واژن, یائسگی, زنان, شیرین بیان, استروژن.

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