The Role of Connective Tissue Genomics in Ascending Aortic Dissection: A Marfan Syndrome Scenario
- سال انتشار: 1398
- محل انتشار: مجله تحقیقات بیهوشی سلولی و مولکولی، دوره: 4، شماره: 3
- کد COI اختصاصی: JR_SBMU-4-3_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 153
نویسندگان
Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Cardiac Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Department of Cardiac Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Anesthesiology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
Anesthesiology Department, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran
چکیده
Background: Aortic dissection is a rare yet life threating condition with some already discovered risk factors namely hypertension, connective tissue disorders such as Marfan syndrome (MFS), cocaine abuse and cigarette smoking.Case report: In this article we would like to present a case of MFS who presented with severe chest pain and undergone Bentall surgery due to aortic dissection and aneurysm.Conclusion: Although many risk factors and preventive measures are already investigated, there is no definite method to avoid its occurrence in genetically predisposed patients such as MFS. Patient-specific models utilizing embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) may offer some advantages.کلیدواژه ها
Aortic Dissection, Marfan Syndrome, Induced Pluripotent Stem Cell; Embryonic Stem Cellاطلاعات بیشتر در مورد COI
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