Variable performance of lncRNA in breast cancer

Introduction: Breast cancer, is one o f most frequent cancers across women, is recognized as a diverse anddifficult disease that continues to be a serious public health problem. Long non coding RNAs have alreadyattracted a lot of interest as a result of the advancement of next generation seq uencing methods. Various studies indicate that long non coding RNAs play an essential part in tumor growth. Even though the biological purpose and molecular processes of long non coding RNAs are still unknown, modern data has shown that a variety of long n on coding RNAs express inappropriately in malignancies, particularly breast cancer. This reviewhighlighted the most recent research on long non coding RNAs in breast cancer, with an emphasis on the manymolecular functions of regulatory long non coding RN As.

کلیدواژه ها:

Breast cancer ، Long non coding RNA ، Cell proliferation ، Molecular mechanisms