Synthesis of metal nanoparticles using differentmicroorganisms

Background and Aim : Today, nanoparticles are very important in the science ofnanobiotechnology Nanoscience has grown and developed in various fields of medicine andtherapy, including cancer treatment. Microorganisms do not need high pressure, temperature andtoxic substances in the synthesis process. Natural microorganisms are bacteria, fungi, yeasts, algae,radionuclides and viruses.Methods : Copper oxide nanoparticles with a diameter of less than ۲۰ nm in doses of ۳۰ and ۶۰μg/ml have relatively good antimicrobial properties and can inhibit the growth of almost allexisting bacteria, especially Escherichia coli bacteria in the sample. The toxicity of silvernanoparticles, which were given orally in doses of ۰.۰۵, ۰.۱ and ۰.۲ ml (۵۰, ۱۰۰ and ۲۰۰microliters) to mice, was studied. Acinetobacter sp. SW۳۰ An ۱۸-h culture grown at ۲.۷ x ۱۰۹cfu/mL could synthesize amorphous nanospheres with a size of ۷۸ nm at ۱.۵ mM and crystallinenanorods at ۲.۰ mM Na۲SeO۳ and beyond.Results : Actinobacteria isolated from different ecosystems are known as potential synthesizers ofgold and silver nanoparticles. S. atrovirens is able to produce silver nanoparticles by extracellularreduction. So far, few studies have reported the use of brown seaweed (seaweed) for the productionof Pd-NPs. By synthesizing and covering Pd-NPs by PB extract, it causes the bioreduction of Pd۲+.Acinetobacter sp. SW۳۰ was found to synthesize intracellular SeNPs, which were characterizedby various physicochemical techniques such as UV-Vis spectroscopy, XRD, SEM, energydispersive X-ray spectroscopy, and TEM. Sathish et al investigated the antibacterial effects ofsilver nanoparticles synthesized by biological method. Also, investigated the antioxidant,antibacterial and anticancer effects of silver nanoparticles produced using Piper longum plantextract.Conclusion : In this article, an attempt has been made to investigate the effects of nanoparticlesynthesis using different microorganisms. Many microorganisms cause better results of treatment,synthesis and production. Check the effects Different microorganisms have been used in thetreatment of breast and lung cancers. For example, copper oxide nanoparticles with a size (lessthan ۲۰ nm) were used to investigate its effect on the genome of Escherichia coli as a model forgram-negative bacteria. The anti-tumor effects of zinc oxide nanoparticles were shown inincreasing the expression of glutathione peroxidase and glutathione reductase genes in MCF-۷breast cancer cell line.

کلیدواژه ها:

Nanoparticles ، Antimicrobial ، anti-tumor ، breast ، lung ، cancer