Study of biofilm formation among S.saprophyticus isolatedfrom patients with UTI

سال انتشار: 1401
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 47

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شناسه ملی سند علمی:

MEDISM23_303

تاریخ نمایه سازی: 16 مهر 1401

چکیده مقاله:

Background and Aim : Urinary tract infection (UTI) is the most frequent bacterial infectionfollowing respiratory tract infections. Gram-negative bacteria, such as Escherichia coli, are themain causative etiologic agents of UTI that accounts for up to ۸۰% of community-acquireduncomplicated UTIs, followed by Klebsiella spp., Enterobacter, and Proteus species.Staphylococcus aureus, Enterococcus spp., and coagulase-negative staphylococci (CoNS) are themost common gram-positive etiologic agents of UTI. Staphylococcus saprophyticus is the mostcommon CoNS which causes uncomplicated urinary tract infections after UropathogenicEscherichia coli (UPEC). The present study aimed to determine biofilm formation in S.saprophyticus strains that cause UTIs in women in Golestan, Iran.Methods : This study was financially supported by a grant from Golestan University of MedicalSciences, Gorgan, Iran. (IR.GOUMS.REC.۱۴۰۱.۰۶۱).A total of ۳۵ S. saprophyticus isolates wereobtained from female patients with UTI. The biofilm formation of S.saprophyticus isolates wascarried out using the conventional method (microtitre plate).Results : Generally, ۲۱(۶۰%) S.saprophyticus isolates were biofilm positive, and among them(۲۹%) isolates showed strong biofilm formation. (۱۸%) showed moderate biofilm formation.Conclusion : In some countries, including Iran, the pathogenicity of S.saprophyticus, is lessstudied. The goal of the present study was to investigate the pattern of biofilm formation amongS.saprophyticus isolated from patients with UTI.

نویسندگان

Maryam Rafiee

Department of Microbiology Golestan University of Medical Sciences, Gorgan, Iran

Ezzat Allah Ghaemi

Department of Microbiology Golestan University of Medical Sciences, Gorgan, Iran