Investigation of frequency and determination of drugsensitivity of Gram-positive bacteria causing septicemia in Inhospitalized patients of HAJAR Hospital, Shahrekord , Chaharmahaland Bakhtiari Province , ۱۴۰۰ .

  • سال انتشار: 1401
  • محل انتشار: بیست و سومین کنگره بین المللی میکروب شناسی ایران
  • کد COI اختصاصی: MEDISM23_197
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 148
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نویسندگان

Atefeh Heidari

Alireza Dehghan

چکیده

Background and Aim : Blood infections are increasingly reported in the world , since Since theyare important diseases, targeted antimicrobial treatment can reduce complications in patients withsepticemia. In order to have a targeted treatment, it is necessary to accurately identify the bacteriaand effective antibiotics for its treatment . Gram-positive bacteria are also one of the causes of thisinfection, research and investigation on these bacteria and identifying the most effective antibioticsfor treatment and ,as a result, reducing mortality are very important. Therefore, the purpose of thisstudy is to investigate the frequency and determine drug sensitivity of Gram-positive bacteriacausing septicemia in hospitalized patients of HAJAR Hospital, Shahrekord , Chaharmahal andBakhtiari Province in ۱۴۰۰ .Methods : In this cross-sectional-retrospective study, all blood cultures referred to Hajar hospitallaboratory from April to March ۱۴۰۰ were examined and studied . Blood cultures were cultured instandard Blood Agar and Chocolate Agar environments and bacterial growth was checked after ۲۴to ۴۸ hours . Based on the type of bacteria grown, antibiotic sensitivity was evaluated on Mueller-Hinton's culture medium in the form of disk diffusion using commercial and standard disks.Finally, the findings were analyzed using descriptive statistics.Results : The results of this study showed that out of ۶۳۷۶ blood cultures, ۱۷۰ samples werepositive (۲.۶۶%). Among them, ۶۷ cases (۳۹.۴۱%) were infected with gram-positive bacteria. Theantibiogram results showed the highest sensitivity to Linezolid (۹۷.۶۲%), rifampin (۸۶.۱۱%),amikacin (۷۳.۶۸%) and cefoxitin (۷۳.۰۸%), respectively. In this study, the most drug resistanceswere erythromycin (۸۴.۰۹%), ciprofloxacin (۵۲.۶۳%) and cefoxitin (۲۵%).Conclusion : Conclusion: According to the results, most gram positive bacteria wereStaphylococcus species. By analyzing antibiotics, it can be said that ciprofloxacin can still be usedfor septicemia caused by gram positives.

کلیدواژه ها

septicemia, gram positive bacteria, blood culture, drug sensitivity

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