Global prevalence and molecular epidemiology of mcrmediatedcolistin resistance in Escherichia coli clinical isolates: asystematic review
- سال انتشار: 1401
- محل انتشار: بیست و سومین کنگره بین المللی میکروب شناسی ایران
- کد COI اختصاصی: MEDISM23_147
- زبان مقاله: انگلیسی
- تعداد مشاهده: 73
نویسندگان
Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
Department of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran
Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
Department of Microbiology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran
Department of Pharmacognosy, School of Pharmacy, Alborz University of Medical Sciences, Karaj, Iran
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
چکیده
Background and Aim : The continuing rise in infections caused by multidrug-resistant (MDR)bacteria is one of the most serious public-health issues in society today. Colistin is a last-resortantimicrobial drug used to treat infections caused by MDR Gram-negative bacteria, thereforeresistance to this antibiotic is extremely hazardous. The current study aimed to evaluate the globalprevalence and distribution of colistin resistance genes among human clinical isolates ofEscherichia coli by systematic review.Methods : PubMed, Embase and Web of Science databases were systematically searched. Forfurther evaluation, all original English language articles that reported colistin resistance in E. coliclinical isolates published between ۲۰۰۰ and ۲۰۲۰ were examined.Results : Of ۴۸۵۷ initial articles, after various stages of review and evaluation ۱۹۰ related articleswere selected for the systematic review. More than ۷۹% of the publications selected in this researchwere published from ۲۰۱۴–۲۰۲۰. In Asia, Europe, America, Africa and Oceania, the prevalenceof mobile colistin resistance (mcr)-harbouring colistin-resistant E. coli was ۶۶.۷۲%, ۲۵.۴۹%,۵.۱۹%, ۲.۲۷% and ۰.۳۲ %, respectively.Conclusion : The recent widespread dissemination of E. coli strains harbouring mcr genesconferring colistin resistance, especially in Asia and Europe, is concerning and requires moreattention.کلیدواژه ها
Escherichia coli, mcr, Colistin, Antibiotic resistance, Systematic reviewاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.