Investigation the effect of Nanohydroxyapatite on Tensile Properties of PHB/nHA Composite Scaffold Used for Bone Tissue Engineering

سال انتشار: 1391
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 1,943

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شناسه ملی سند علمی:

NAMIC01_061

تاریخ نمایه سازی: 18 تیر 1391

چکیده مقاله:

In This study Hydroxyapatite nanoparticles (nHA) was synthesized via sol-gel method and Poly 3-hydroxybutyrate/Hydroxyapatite (PHB/HA) Nanocomposite scaffolds were prepared by solvent casting and particulate leaching Technique. Synthesized NanoHA was confirmed by XRD . The scaffolds were prepared from 4%wt polymer solution. amount of nHA was 0-10%wt with 80%wt salt (NaCl) particles. Scanning electron microscopy (SEM) was used for study structure of prepared scaffolds and size of nHA particles. uniform distribution of NanoHA in scaffolds were investigated by Wavelength Dispersive X-ray Spectroscopy (WDXA). pore size was in range of 200-250μm. Tensile strength and elastic modulus increased by increasing the amount of nHA in scaffolds.

کلیدواژه ها:

PHB/nHA composite scaffolds - bone tissue engineering- tensile properties

نویسندگان

A. Saadat

Department of Materials Engineering, Majlesi Branch, Islamic Azad University, Isfahan, Iran

A. behnamghader

Biomaterials group, Materials & Energy Research Center, Tehran, Islamic Republic of Iran, Postal code ۱۳۱۴۵-۱۶۵۹

S. karbasi

Department of Medical Physics and Biomedical engineering, Isfahan University of Medical Science Isfahan, Iran

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