Post Cesarean Section Analgesic Effects of Intravenous Pethidine and Diclofenac Suppository after Spinal Anesthesia: A Randomized Clinical Trial

  • سال انتشار: 1401
  • محل انتشار: مجله علوم دارویی و شیمی، دوره: 5، شماره: 7
  • کد COI اختصاصی: JR_JMCH-5-7_002
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 91
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نویسندگان

Pourya Adibi

Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Majid Vatankhah

Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Mehrdad Malekshoar

Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Bibi Mona Razavi

Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

Tayyebeh Zarei

Anesthesiology, Critical Care and Pain Management Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran

چکیده

Introduction: One of the most difficult challenges after a C-section is minimizing pain. The goal of this study was to see how intravenous pethidine and diclofenac suppository altered pain following a cesarean section performed under spinal anesthesia.Methods: In this randomized clinical trial on elective cesarean section candidates, patients were randomly assigned to one of two groups receiving intravenous pethidine or diclofenac suppository. Patients' pain was scored using the Visual Analogue Scale (VAS) pain measuring instrument at different times of entry to the recovery room, ۳۰ and ۶۰ minutes in recovery and ۲, ۴ and ۶ hours after surgery.Results: The incidence of pain (VAS> ۳) in groups receiving pethidine or diclofenac was significantly different at ۳۰ and ۶۰ minutes of entering recovery room. Therefore, more pain was reported in the group receiving pethidine (P-value = ۰.۰۰۱ and P-value = ۰.۰۱۴). However, there was no significant differences in other periods analyzed.Conclusion: Diclofenac suppository greatly lowers the occurrence of pain after cesarean section compared with intravenous pethidine and has a more appropriate effect, according to the findings of this study. Therefore, it is recommended to use diclofenac suppository to reduce the incidence of pain in patient who have undergone cesarean section.

کلیدواژه ها

Pethidine, Diclofenac, Pain, Cesarean section

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