The effect of exercise on metabolic syndrome and related diseases

The prevalence of over weight and obesity in most developing countries is concerning. Obesity or overweight is physiologically defined as the accumulation of excess fat in adipose tissue, which may cause some serious health concerns. Obesity increases the risk of metabolic syndrome (MS). Metabolic syndrome is a combination of risk factors for cardiovascular disease (CVD) and type ۲ diabetes (T۲D). There are five screening variables to identify people with metabolic syndrom: waist circumference (WC), circulating triglyceride (TG) and high-density lipoprotein (HDL) levels, cholesterol, fasting blood glucose (FBS) and blood pressure (BP). Therefore, metabolic syndrome can be considered as a set of metabolic risk factors that include obesity and dyslipidemia, insulin resistance and hypertension. The relationship between obesity, insulin resistance and hypertension has been investigated and proven in many studies. It has also been suggested that increased physical activity and exercise can play an important role in preventing metabolic syndrome and related chronic diseases such as type ۲ diabetes, hypertension and other metabolic disorders by controlling or even improving obesity, insulin resistance and blood presure. Various mechanisms regarding metabolic syndrome and disease risk factors has been mentioned in current study. In this review, we persent recearch-based evidence supporting the potential effects of exercise on metabolic syndrome and related diseases. We also discuss intracellular mechanisms in some sections. Finally, studies reviewed in the current study supports the general idea that physical activity can be used as a practical method in controlling or even improving the risk factors of metabolic syndrome and associated diseases.

کلیدواژه ها:

metabolic syndrome ، Dyslipidemia ، Type ۲ diabetes ، Hypertension ، Exercise activity