The effect of acute noise stress on coagulation responses in trained rats with intermittent and continuous exercise training

Stimulation of biological responses by internal or external stimuli & quot;stress& quot; and compensatory responses to it are known as stress responses. Depending on the type and intensity of stress stimuli can affect various body systems such as coagulation factors. Prothrombosis and fibrinolysis increase during psychological stress, which may increase the risk of platelet dysfunction during stress. Major coagulation and fibrinolytic factors such as tpA, PAI۱, Pt, Ptt, plasminogen, fibrinogen, and D are also involved.The aim of the present study was to investigate the effect of acute vocal stress session on the response of coagulation factors in rats compatible with both types of exercise. Forty-two male Wistar rats were randomly divided into ۷ groups of ۱۰, including: control group (C), time control group (CT), acute acoustic stress group (S), high-intensity intermittent exercise group (HIIT) and moderate-intensity continuous exercise ( MCT), continuous training group and then acute vocal stress (HIIT + S), continuous training group with moderate intensity and acute vocal stress (MCT + S).Exercise groups (MCT, HIIT, MCT + S, HIIT + S) performed the exercises for ۸ weeks. The vocal stress groups (HIIT + S, MCT + S and S) were placed in one vocal stress session. ۴۸ hours after the last exercise session (HIIT, MCT) and simultaneously in CT groups and immediately after vocal stress in three stress groups, blood samples were taken. (Blood sample from group C at the beginning of the study).The results showed that due to the effect of two types of exercise (without stress), the amount of prothrombin in the MCT group was significantly higher than the HIIT group. But there was no significant difference between training and control groups and time control and initial control.By comparing the stress groups, serum corticosterone levels in the HIIT + S group were higher than in the MCT + S group and the MCT + S group were higher than in the stress group. However, after training adaptations and in stressful situations, it has a higher stress response, and high-intensity intermittent exercise can not moderate the negative effects of acoustic stress on prothrombin levels.

کلیدواژه ها:

Acute vocal stress ، Blood coagulation factors ، corticosterone ، periodic and continuous exercise