ASSESSMENT OF RELATION BETWEEN MICROALBUMINURIA AND ISCHEMIC ELECTROCARDIOGRAM IN IRANIAN GENERAL POPULATION

سال انتشار: 1388
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 23

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شناسه ملی سند علمی:

JR_RYA-5-1_006

تاریخ نمایه سازی: 3 شهریور 1401

چکیده مقاله:

Abstract    BACKGROUND: Enhancement of albumin exertion in urine increases the risk of renal and ischemic heart diseases (IHD). We assessed the association of urine albumin and sub-clinical IHD in a random sample of Iranian general population.    METHODS: The random sample in general population in Isfahan County was recruited to the cross-sectional study. From the all sample blood pressure and lipid profile were assessed and morning urine spot was measured for albumin and Creatinine. Microalbuminuria was defined either Albumin-Creatinine Ratio (ACR) was ۳۰-۳۰۰mg. Also, the standard ۱۲ lead electrocardiogram (ECG) was carried out for all participants. The ECG pattern was divided to two categories; normal or ECG with ischemia. The logistic regression model was determined the odds of albuminuria for ischemic changes in ECG.    RESULTS: ۹۹۹ subjects, age ۳۵-۷۰ years, participated to study. From all, ۴۰.۸% were male. Microalbuminuria was detected in ۸% and sub-clinical ECG ischemic changes were found in ۲۳.۴%. The most frequent ischemic change was T wave inversion. The mean urine albumin levels in subjects with normal ECG was ۹.۶±۱۴.۶ mg/ml and in ischemic group was ۸.۵±۱۲.۲ mg/ml and they did not have statistically different. The odds ratios of neither Albumin-Creatinine ratio nor microalbuminuria were in significant range for risk to ischemic changes in ECG of apparently healthy participants. They was consecutively OR=۰.۹ (۰.۵۱-۱.۶), OR=۰.۹۹ (۰.۹۸-۱.۰۰۴).     CONCLUSION: Our finding didn’t declare any association between ACR and IHD. Because of showing this association in the other study; it needs more exploration regarding to association between microalbuminuria and cardiovascular diseases incidence.      Keywords: Ischemic heart diseases, electrocardiogram, Albumin-Creatinine Ratio, Urine Albumin

نویسندگان

Alireza Khosravi

Assistant professor of Cardiology. Isfahan Cardiovascular Research Center. Isfahan University of Medical Sciences, Isfahan.

Leili Avesta

Resident of Cardiology. Department of Cardiology. Isfahan University of Medical Sciences, Isfahan.

Roya Kelishadi

Associated professor of Pediatrics. Isfahan Cardiovascular Research Center. Isfahan University of Medical Sciences, Isfahan.

Mohammad Arash Ramezani

Head of Surveillance Department. Isfahan Cardiovascular Research Center. Isfahan University of Medical Sciences, Isfahan.

Ahmad Bahonar

Executive manager. Isfahan Cardiovascular Research Center. Isfahan University of Medical Sciences, Isfahan.

Hossein Heydari

Isfahan Cardiovascular Research Center. Isfahan University of Medical Sciences, Isfahan.

Aliakbar Tavassoli

Associated professor of Cardiology. Department of Cardiology. Isfahan University of Medical Sciences, Isfahan.

Nizal Sarrafzadegan

Professor of Cardiology. Head of Isfahan Cardiovascular Research Center. Isfahan University of Medical Sciences, Isfahan.