ASSESSMENT OF ANTIOXIDANT NUTRIENT INTAKE AND MALONDIADEHYDE PLASMA LEVEL IN RHEUMATOID ARTHRITIS

  • سال انتشار: 1388
  • محل انتشار: مجله آریا آترواسکلروز، دوره: 5، شماره: 1
  • کد COI اختصاصی: JR_RYA-5-1_001
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 107
دانلود فایل این مقاله

نویسندگان

Yousef Shaabani

Msc, School of Nutrition and Food Sciences, Shaheed Beheshti University of Medical Sciences, Tehran.

Maryam Foroughi

Msc, School of Health, Teharan University of Medical Science, Tehran.

Reza Rastmanesh

Assistant Professor, Department of Human Nutrition, School of Nutrition and Food Sciences, Tehran.

Ahmadreza Jamshidi

Associate Professor, Rheumatology Research Center, Teharan University of Medical Science, Tehran.

Narges Tajik

Msc, School of Health, Teharan University of Medical Science, Tehran.

Omid Assadi

Bsc, School of Nutrition and Food Sciences, Shaheed Beheshti University of Medical Sciences, Tehran.

چکیده

Abstract    BACKGROUND: Elevated free radical generation in inflamed joints and impaired antioxidant systems have been implicated in rheumatoid arthritis (RA). The present study was performed to evaluate dietary nutrient intake and plasma oxidant status in RA patients.    METHODS: This case-control study comprised ۷۵ RA patients and equal number of age- and gender-matched controls. Nutrient intake was estimated by using a semi-quantitative food frequency questionnaire. Blood samples were obtained from each group, and as an indicator of oxidant status, plasma concentrations of malondiadehyde (MDA) were measured.    RESULTS: The mean calorie intake of RA patients was lower than that of the healthy controls. Energy-adjusted intake of fat, vitamin A and ß-carotene were significantly lower in patients than in control .Plasma MDA concentration was significantly higher in RA patients than in controls (۴.۹±۱.۸ vs ۲.۱±۰.۶ nmoles/ml respectively, P < ۰.۰۱).    CONCLUSION: These results suggest proper antioxidant nutrient intake management may reduce free radical generation and improve antioxidant status in RA patients.      Keywords: rheumatoid arthritis, antioxidant, malondialdehyde.

کلیدواژه ها

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.