Is responsiveness to weight loss diets affected by family history of diabetes?

  • سال انتشار: 1393
  • محل انتشار: مجله آریا آترواسکلروز، دوره: 10، شماره: 3
  • کد COI اختصاصی: JR_RYA-10-3_006
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 156
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نویسندگان

Behnaz Nikkar

Salamat Iranian Clinic, Isfahan, Iran

Hossein Khosravi-Boroujeni

Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran AND Griffith Health Institute, Griffith University, Gold Coast, QLD, Australia

Majid Kolahdouzan

Salamat Iranian Clinic, Isfahan, Iran

Marzieh Ghoreishyan

Salamat Iranian Clinic, Isfahan, Iran

Samarghand Ebadi

Salamat Iranian Clinic, Isfahan, Iran

Asieh Mohamadzadeh

Salamat Iranian Clinic, Isfahan, Iran

Mahnaz Soghrati

Salamat Iranian Clinic, Isfahan, Iran

Shaghayegh Sayareh

Salamat Iranian Clinic, Isfahan, Iran

چکیده

BACKGROUND: Obesity is associated with many metabolic and chronic diseases, such as diabetes and cardiovascular disease. Family history of diabetes (FHD) is also an important risk factor for type ۲ diabetes. Furthermore, the presence of FHD and obesity has a synergic effect on risk of diabetes incidence. The aim of this study was to determine whether FHD influence the weight loss induced by weight loss diet. METHODS: This study was an intervention between individuals with or without FHD. Seventy-eight positive FHD and ۷۴ negative FHD individuals were participated in this study. Two groups were matched for age, gender, and body mass index (BMI). In the present study, expert interviewers collected socio-demographic data and prescribed dietary recommendations in a face-to-face method. RESULTS: Dietary intervention significantly reduces the body weight and BMI in both groups, but these reductions were not different between negative and positive FHD groups. This study could not find any significant association between FHD and responsiveness to weight loss diets (β = −۰.۰۵۸; ۹۵% confidence interval, −۱.۶۱۸ to ۰.۸۳۲; P = ۰.۵۲۶). CONCLUSION: Individuals with FHD have higher risk for obesity and chronic diseases, but in the current study there was no difference in responsiveness to weight loss in individuals with a positive family history and those without a family history.   Keywords: Body Weight, Body Mass Index, Weight Loss Diet, Family History of Diabetes 

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