Acute myocardial infarction in very young adults: A clinical presentation, risk factors, hospital outcome index, and their angiographic characteristics in North India - AMIYA Study

  • سال انتشار: 1396
  • محل انتشار: مجله آریا آترواسکلروز، دوره: 13، شماره: 2
  • کد COI اختصاصی: JR_RYA-13-2_005
  • زبان مقاله: انگلیسی
  • تعداد مشاهده: 143
دانلود فایل این مقاله

نویسندگان

Santosh Sinha

Assistant Professor, Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Vinay Krishna

Assistant Professor, Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Ramesh Thakur

Professor, Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Ashutosh Kumar

Senior Researcher, Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Vikas Mishra

Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Mukesh Jha

Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Karandeep Singh

Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Mohit Sachan

Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Rupesh Sinha

Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Mohammad Asif

Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Nasar Afdaali

Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

Chandra Varma

Professor, Department of Cardiology, Laxmipat Singhania (LPS) Institute of Cardiology, Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India

چکیده

BACKGROUND: India is currently in the fourth stage of epidemiological transitions where cardiovascular disease is the leading cause of mortality and morbidity. Purpose of the present study was to assess the risk factors, clinical presentation, angiographic profile including severity, and in-hospital outcome of very young adults (aged ≤ ۳۰ years) with first acute myocardial infarction (AMI). METHODS: Total of ۱,۱۱۶ consecutive patients with ST-segment elevation acute myocardial infarction (STEMI) were studied between March ۲۰۱۳ and February ۲۰۱۵ at LPS Institute of Cardiology, Kanpur, Uttar Pradesh, India. RESULTS: Mean age of the patients was ۲۶.۳ years. Risk factors were smoking (۷۸.۵%), family history of premature coronary artery disease (CAD) (۴۶.۸%), obesity (۳۹.۱%), physical inactivity (۳۸.۷%) and stressful life events (۲۹.۶%). The most common symptom and presentation was chest pain and anterior wall MI (AWMI) in ۹۴.۸% and ۵۸.۸%, respectively. About ۸۰.۶% of patients had obstructive CAD with single vessel disease (۵۷.۶%), double-vessel disease (۱۲.۹%) and left main involvement (۳.۲%). Left anterior descending (LAD) was commonest culprit artery (۵۸.۱%) followed by right coronary artery in ۲۸.۲%. In-hospital mortality was ۲.۸%. Percutaneous coronary intervention was performed in ۷۱.۶% of patients. Median number and length of stent were ۱.۱۸ and ۲۸ ± ۱۶ mm, respectively. CONCLUSION: AMI in very young adult occurred most commonly in male. Smoking was the most common risk factor. AWMI owing to LAD artery involvement was the most common presentation. Mean time of presentation after symptom onset was ۱۶.۹ hours. In contrast to western population, it is characterised by earlier onset, delayed presentation, more severity, diffuse disease, and more morbidity but with favourable in-hospital mortality 

کلیدواژه ها

Myocardial Infarction, Angiography, Percutaneous Coronary Intervention, Young Adults

اطلاعات بیشتر در مورد COI

COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.

کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.