Comparison of four types of vaccines Sinopharm, AstraZeneca, Sputnik V, and Covaxin in terms of morbidity and severity of COVID-۱۹ in vaccinated personnel of several selected medical centers, Tehran, Iran
- سال انتشار: 1401
- محل انتشار: فصلنامه بین المللی تحقیقات پزشکی، دوره: 11، شماره: 2
- کد COI اختصاصی: JR_INTJMI-11-2_009
- زبان مقاله: انگلیسی
- تعداد مشاهده: 276
نویسندگان
Mazandaran University of Medical Sciences , Sari , Iran
Ph.D. in pediatrics, Infectious Diseases Research Center, Aja University of Medical Sciences, Tehran, Iran,
Mohammad Hassan Kazemi-Galougahi
Ph.D. in Epidemiology Faculty of Medicine, Aja University of Medical Sciences, Tehran, Iran
Ph.D. in Nursing, Faculty of Nursing, Aja University of Medical Sciences, Tehran, Iran
Master of sciences in nursing, faculty of nursing, Aja University of Medical Sciences, Tehran, Iran,
BSN Nursing student, Aja University of Medical Sciences, Tehran, Iran,
Mazandaran University of Medical Sciences, Sari, Iran
Mazandaran University of Medical Sciences , Sari ,Iran
Mazandaran University of Medical Sciences, Sari, Iran
Assistant professor of pediatrics Dep, Faculty of Medicine Trauma Research center, Aja University of Medical Sciences, Tehran, Iran,
چکیده
Abstract BACKGROUND: The main purpose of the present study was to compare four vaccines: Sinopharm, AstraZeneca, Sputnik V, and Covaxin, in terms of morbidity and severity of COVID-۱۹ after vaccination in healthcare workers working in selected medical centers in Tehran, Iran. MATERIALS AND METHODS: This descriptive-analytical cross-sectional study was conducted among ۱۴۷۴ students, staff of a medical university, and seven selected hospitals in Tehran for two months between June to August ۲۰۲۱; Data were collected by a questionnaire, Participants had received one or two doses of mentioned vaccines and at least twenty days had passed since they received their first dose of the vaccine. Incomplete questionnaires were excluded from statistical analysis. RESULTS: ۳۵.۹% (n=۵۳۱) of participants had a history of COVID-۱۹ before vaccination. There was no significant relationship between the history of the previous infection with COVID-۱۹ before vaccination and the occurrence of COVID-۱۹ after vaccination in any of the vaccines. For all four vaccines, the occurrence of the disease after receiving the second dose was less than ۱۰% (Sinopharm ۳.۱%, AstraZeneca ۶.۴%, Sputnik V ۶.۴%, Covaxin ۶.۸%),. There was a statistically significant difference among all vaccines mentioned above in terms of COVID-۱۹ infection after receiving the second dose (p = ۰.۰۴۲) for all four vaccines. The severe form of the disease, which requires referral to medical centers, was less than ۱۰% among patients with the disease after vaccination. There was no significant difference between the vaccines regarding disease severity in patients. CONCLUSION: The severity of COVID-۱۹ was not significantly different in the infected patients after the first or second dose. Also, the previous infection with COVID-۱۹ before vaccination was not associated with the occurrence of COVID-۱۹ after vaccination in any of the four vaccines. To sum up, this finding can be applied by policymakers to have a better vision.کلیدواژه ها
Vaccination, Covid-۱۹, Severity, Morbidity, Immunityاطلاعات بیشتر در مورد COI
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