Cardiac involvement according to echocardiographic findings in severe coronavirus disease ۲۰۱۹

BACKGROUND: Coronavirus disease ۲۰۱۹ (COVID-۱۹) has led to considerable morbidity and mortality worldwide and myocardial injury has been one of the most common findings in the affected patients. However, published evidence of cardiac evaluation by imaging techniques including echocardiography is rare. We aimed to evaluate myocardial involvement by echocardiography in patients with severe COVID-۱۹.METHODS: We studied ۶۴ patients with severe COVID-۱۹ who were admitted in the intensive care unit (ICU) in Khorshid Hospital, Isfahan, Iran, from February ۲۰, ۲۰۲۰ until May ۲۰, ۲۰۲۰. Demographic characteristics, laboratory tests, and electrocardiography (ECG) data were collected and transthoracic echocardiography (TTE) using a focused time-efficient echocardiography protocol was performed.RESULTS: Mean age of the participating patients was ۶۶.۴۰ ± ۱۴.۱۴ years (range: ۳۴.۰-۹۲.۰ years), and ۳۵ patients (۵۴.۷%) were men. Reduced left ventricular (LV) systolic function was seen in ۲۰ (۳۲%) patients. Only ۴ patients had LV ejection fraction (LVEF) less than ۴۰%. Cardiac troponin I (cTn-I) was elevated (over ۱۵ pg/ml) in ۳۹ (۶۰.۹%) patients and was significantly associated with higher mortality in these patients (P = ۰.۰۵). In addition, dynamic ST and T wave changes and new bundle branch blocks had a significant association with adverse clinical outcome (P = ۰.۰۵ and P = ۰.۰۲, respectively).CONCLUSION: New LV systolic dysfunction (LVSD) in patients with severe COVID-۱۹ was mild to moderate and not uncommon and had no significant adverse effect on the prognosis of these patients, although elevation of cardiac biomarkers could predict mortality and had an adverse effect on clinical outcome.

کلیدواژه ها:

Echocardiography ، Coronavirus Disease ۲۰۱۹ ، Cardiac Involvement