Lactobacilli and Bifidobacterium as anti- atherosclerotic agents
- سال انتشار: 1401
- محل انتشار: مجله علوم پایه پزشکی ایران، دوره: 25، شماره: 8
- کد COI اختصاصی: JR_IJBMS-25-8_002
- زبان مقاله: انگلیسی
- تعداد مشاهده: 188
نویسندگان
Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman, Iran
Hadi Esmaeili Gouvarchin Ghaleh
Applied Virology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Molecular Biology Research Center, Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran
چکیده
Atherosclerosis is the thickening or hardening of the arteries which is caused by a buildup of atheromatous plaque in the inner lining of an artery. Hypercholesterolemia, inflammation, oxidative stress, and trimethylamine N-oxide (TMAO) are important risk factors for atherosclerosis. Therefore, this study aimed to review the anti-atherosclerotic effects of Lactobacilli and Bifidobacterium via improving lipid profile and reducing the effects of oxidative stress, inflammation, and TMAO. To prepare the present review, several databases such as Scopus, PubMed, and Google Scholar were searched, and relevant articles from ۱۹۹۰ until ۲۰۲۲ were selected and reviewed. The present review showed that Lactobacilli and Bifidobacterium reduce the risk of atherosclerosis in both in vitro and in vivo studies by breaking down or altering cholesterol metabolism with the help of their by-products and by reducing inflammation and oxidative stress and TMAO. Consumption of Lactobacilli and Bifidobacterium can be useful in prevention of atherosclerosis.کلیدواژه ها
Atherosclerosis, Bifidobacterium, Hypercholesterolemia, Inflammation, Lactobacilli, Oxidative stress, TMAOاطلاعات بیشتر در مورد COI
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