The relation between vitamin D status and anemia in patients with end stage renal disease on regular hemodialysis
- سال انتشار: 1400
- محل انتشار: مجله رنال آندوکرینولوژی، دوره: 7، شماره: 1
- کد COI اختصاصی: JR_JRE-7-1_015
- زبان مقاله: انگلیسی
- تعداد مشاهده: 328
نویسندگان
Department of Internal Medicine and Nephrology, Ain Shams University, Cairo, Egypt
Department of Internal Medicine and Nephrology, Ain Shams University, Cairo, Egypt
Essam Eldin Rashad Saeed Abdulkhalek
Cairo University, Cairo, Egypt
Department of Internal Medicine and Nephrology, Ain Shams University, Cairo, Egypt
چکیده
Introduction: Anemia is a common complication in end-stage renal disease (ESRD) patients on regular hemodialysis (HD). There has been a lot of interest recently in the non-classical effects of ۲۵(OH) vitamin D (calcidiol), including its association with erythropoiesis and anemia pathogenesis.Objectives: To study the relation between anemia and vitamin D status in patients on regular HD.Patient and Methods: This study is a cross-sectional study that included ۹۰ patients on regular HD. Vitamin D status was classified into deficient (< ۲۰ ng/mL), insufficient (۲۰-۳۰ ng/mL) and sufficient (> ۳۰ ng/mL).Results: The level of vitamin D measured in the patients ranged between ۳.۵ to ۶۶ ng/mL with median of ۱۶.۳۵ ng/mL. There were statistically significant positive correlations between vitamin D levels and the level of hemoglobin (P < ۰.۰۰۱), serum calcium levels (P < ۰.۰۰۱) and serum PO۴ levels (P = ۰.۰۲۳). Higher hemoglobin levels were statistically related to both higher vitamin D values (P < ۰.۰۰۱) and higher serum calcium concentration (P < ۰.۰۰۱). Meanwhile, a significant negative correlation was found between hemoglobin levels and serum PTH values (P < ۰.۰۰۱).Conclusion: There was a significant association between the status of vitamin D and the level of hemoglobin in dialysis population who were studied, independent from iron status. other associations with hemoglobin levels included PTH level and calcium.کلیدواژه ها
Vitamin D, Calcidiol, Anemia, Dialysis, End-stage renal diseaseمقالات مرتبط جدید
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