Oxidative stress in chronic kidney disease; an updated review on current concepts
- سال انتشار: 1396
- محل انتشار: مجله رنال آندوکرینولوژی، دوره: 3، شماره: 1
- کد COI اختصاصی: JR_JRE-3-1_001
- زبان مقاله: انگلیسی
- تعداد مشاهده: 302
نویسندگان
School of Nutrition & Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده
Chronic renal failure is associated with enhanced oxidative stress. Oxidative stress has been implicated in various pathological systems that are prevalent in both chronic kidney disease (CKD) and cardiovascular disease, most importantly are inflammation and fibrosis. Chronic inflammation is provoked by oxidative stress and chronic degenerative diseases. The inflammatory cells are source of free radicals in the forms of reactive oxygen (O۲) and nitrogen species, while reactive oxygen species (ROS) are considered as the most responsible factor in CKD. ROS are able to be harmful in a variety of functional and structures pathways in cells. Oxidative stress rises free radicals are general product of normal aerobic cellular metabolism. While, O۲ is vital for life, imbalanced metabolism and excess ROS generation lead into a range of disorders such as CKD. The purpose of this review is to provide an overview of development of oxidative stress, biomarkers, the involvement of mitochondrial dysfunction and the molecular pathways of oxidative stress in CKD.کلیدواژه ها
Oxidative stress, Chronic kidney disease, Chronic inflammation, Free radicals, Reactive oxygen speciesمقالات مرتبط جدید
- مقایسه سمیت حاد متانول و اتانول در گاماروس آب شیرین Gammaruspseudosyriacus
- Post-COVID–۱۹ complication and its effect on acute kidney injury
- Effect of oral vitamin C on serum hepcidin level, iron status and inflammation among hemodialysis patients with functional iron deficiency anaemia
- The relation between vitamin D status and anemia in patients with end stage renal disease on regular hemodialysis
- Outbreak and impact of coronavirus disease ۲۰۱۹ (COVID-۱۹) on dialysis patients; Al Khezam dialysis center experience, Kuwait
اطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.