Firooze Niazvand - School of medicine, Abadan Faculty of Medical Sciences, Abadan, Iran
Pushkaraj Rajendra Wagh - Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA, United States
Elham Khazraei - Department of Chemical Engineering, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran
Mahsa Borzouyan Dastjerdi - Department of Stem Cells and Regenerative Medicine, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran
Chanakya Patfil - Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, USA
Ishtiyaq Najar - School Education Department, UT of Jammu and Kashmir, India

In recent years, various drug carrier nanomaterials have been investigated to improve drug delivery systems in cancer treatment. However, an ongoing requirement exists for more beneficial therapeutic materials, yielding rapid clearance, high capacity for reducing systemic toxicity via specific-tumor targeting, and superior drug solubility. Given that, carbon allotropes, including Active Carbon (AC), carbon nanotubes (CNTs), graphene and graphene oxides (GOs), nanodiamonds (NDs), fullerenes, carbon nanohorns, soporous carbons, and carbon dots, have been studied owing to their high thermal conductivity, rigid structure, flexibility for modification and functionalization, adequate surface-to-volume ratio, and high biocompatibility. This review aims to overview recent advances in applying different carbon allotrope composites in drug delivery-based cancer therapy systems.

Carbon allotropes, Drug delivery, Cancer therapy, NanocompositesNanomaterials