Corticosteroid Therapy for ۲۰۱۹ Novel Coronavirus: Lessons From SARS and MERS

سال انتشار: 1400
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 87

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شناسه ملی سند علمی:

JR_JCMI-8-4_005

تاریخ نمایه سازی: 30 مرداد 1401

چکیده مقاله:

For the last three decades, the world population has experienced new epidemics of coronaviruses. The worldis currently witnessing the novel coronavirus disease (COVID-۱۹) epidemic, which is a disease that comesfrom a novel coronavirus called Severe acute respiratory syndrome coronavirus ۲ (SARS-CoV-۲). The availablegenetic and clinical proofs suggest a similar route to those of Middle East respiratory syndrome (MERS) andSARS. The clinical manifestations of infections caused by coronaviruses including SARS, MERS, and COVID-۱۹are pneumonia, bronchitis, or other serious respiratory infections. Various transmission ways (e.g., nosocomialtransmission) and transmission through moderately symptomatic or non-symptomatic infected individualshave caused great concerns. Although no certain treatment has so far been developed for this disease, andprevention is the main applied strategy for these viruses, some medications can be used to help with this disease.Corticosteroids can be mentioned as an example of these medications. This article specifically reviewed theevidence regarding the effectiveness of the corticosteroid therapy for the coronavirus family (i.e., SARS, MERS,and COVID-۱۹) and showed that there are insufficient data to recommend corticosteroid therapy for patientssuffering from COVID-۱۹.

نویسندگان

Mobina Fathi

Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Kimia Vakili

Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Ramtin Hajibeygi

Department of Cardiology, Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

Niloofar Deravi

Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Arian Tavasol

Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Shirin Yaghoobpoor

Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran