Serum Magnesium Levels in Children with Type ۱ Diabetes Mellitus in Northwest Iran
محل انتشار: مجله بین المللی کودکان، دوره: 10، شماره: 6
سال انتشار: 1401
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 125
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شناسه ملی سند علمی:
JR_INJPM-10-6_012
تاریخ نمایه سازی: 11 تیر 1401
چکیده مقاله:
Background: Type ۱ Diabetes Mellitus (T۱DM) is a chronic disorder that can cause microvascular and macrovascular damages in the long term as well as higher rates of mortality and morbidity in infectious diseases such as Covid-۱۹. It has been discovered that the homeostasis of trace electrolytes like magnesium plays a crucial role in the pathogenesis of diabetes and its related complications. We aimed to determine serum magnesium levels in children with T۱DM in northwest Iran and to evaluate the relationship between serum magnesium levels and glycemic control while also assessing several anthropometric and birth-time-related factors. Methods: This cross-sectional study gathered data from ۵۰ patients with T۱DM and ۵۰ other healthy subjects matched for age and gender living in the northwest area of Iran. These children were tested during their visits to the children’s hospital of Tabriz. Magnesium levels and environmental factors were measured in all study subjects. Results: We found magnesium levels to be significantly lower in children with T۱DM (p < ۰.۰۰۱). Hypomagnesemia was also seen in ۵۸% of the case group, which was significantly more prevalent than the ۶% in the control group (p <.۰۰۱). We observed a negative correlation between serum magnesium and HbA۱c levels in the diabetic group (r = -۰.۸۸۲, p <.۰۰۱). No significant correlation was found between magnesium levels and duration of diabetes, age, and gender. Conclusion: We concluded that total serum magnesium is lower in children with T۱DM, which correlates with glycemic control. Further and more extended studies should be conducted to assess the effect of correction of serum magnesium in diabetic children with hypomagnesemia on glycemic control and the risk of diabetic complications.
کلیدواژه ها:
نویسندگان
Lida Saboktakin
Pediatrics Health Research Center, Department of Pediatrics, Tabriz University of Medical Sciences, Tabriz, Iran
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