The Design of Soft Drugs: Basic Principles, Energetic Metabolite Methods, Approved Compounds, and Pharmaceutical Applications
- سال انتشار: 1401
- محل انتشار: فصلنامه مروری شیمی، دوره: 4، شماره: 3
- کد COI اختصاصی: JR_JCHM-4-3_003
- زبان مقاله: انگلیسی
- تعداد مشاهده: 153
نویسندگان
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K. R. Palli Cross, Ananthapuramu-۵۱۵۷۲۱, Andhra Pradesh, India
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K. R. Palli Cross, Ananthapuramu-۵۱۵۷۲۱, Andhra Pradesh, India
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K. R. Palli Cross, Ananthapuramu-۵۱۵۷۲۱, Andhra Pradesh, India
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K. R. Palli Cross, Ananthapuramu-۵۱۵۷۲۱, Andhra Pradesh, India
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K. R. Palli Cross, Ananthapuramu-۵۱۵۷۲۱, Andhra Pradesh, India
Department of Industrial Pharmacy, Raghavendra Institute of Pharmaceutical Education and Research (RIPER)-Autonomous, K. R. Palli Cross, Ananthapuramu-۵۱۵۷۲۱, Andhra Pradesh, India
چکیده
This work explores soft drugs and their configuration for drug delivery. Compared with the stimulated soft compound, soft drugs have a fast metabolism and exert their therapeutic effects. They are organically active drugs, carefully formulated to have a predictable and controllable absorption near harmless compared with sedentary products. The broader neurometabolic drug plan concept depends on the soft drug configuration. This is usually accomplished by using close analogues of proven lead compounds and an ester as a metabolically delicate weakness. A rationally designed or accidentally developed soft drug has proven clinically useful. The idea of neurometabolic drug plans relies upon the configuration of soft drugs. This method is immensely flexible and can be implemented to create inventive, new substances in a widespread helpful field. A metabolically, especially hydrolytically labile moiety, is attached to the construction to control and direct digestion.کلیدواژه ها
Antidrug, Drug, Metabolism, Soft drug, Therapeutic indexاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.