An Ethnomedicinal Plant: Antibacterial Activities of Stachys Lavandulifolia Vahl Aqueous Extract against Common Pathogens
- سال انتشار: 1400
- محل انتشار: دوفصلنامه بیوتکنولوژی گیاهی، دوره: 3، شماره: 1
- کد COI اختصاصی: JR_PBP-3-1_001
- زبان مقاله: انگلیسی
- تعداد مشاهده: 222
نویسندگان
۱ Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran۲ Department of Clinical Biochemistry, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran
Department of Dermatology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran
Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran
Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran
Department of Microbiology section, Pathobiology & Basic Sciences, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran.
Department of Clinical Sciences, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran
Department of Microbiology section, Pathobiology & Basic Sciences, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran
Department of Clinical Sciences, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran
چکیده
Enhancing microbial resistance to antibiotics and their probable side effects leads to the popularity of medicinal plants, so the need for novel antibacterial compounds with plant origin is felt more than ever. The object of the present study was to assess the antibacterial property of Stachys lavandulifolia Vahl aqueous extract (SLVAE) on Escherichia coli O۱۵۷:H۷ (EC), Pseudomonas aeruginosa (PA), Staphylococcus aureus (SA) and Bacillus subtilis (BS). The aqueous extract was obtained using a rotary evaporator. Agar disk and well diffusion methods were used to investigate the antibacterial property of the SLVAE. In the agar disk diffusion test, distilled water was used as a negative control whereas streptomycin, oxytetracycline, gentamicin, difloxacin, chloramphenicol, ampicillin, and amikacin were used as positive controls. Macro broth tube test was accomplished to specified Minimum Inhibitory Concentration (MIC). Statistical comparison among groups means were done through one-way ANOVA followed by Duncan’s post-hoc test. P ≤ ۰.۰۱ was considered as significant. Indeed compared with many standard antibiotics, the extract showed the higher antibacterial property. Also SLVAE with ۱۲۵, ۱۵/۶۲ and ۷/۸۱ mg/mL concentrations has prevented the growth of EC, SA/BS and PA, respectively, and with ۱۲۵, ۶۲/۵ and ۱۵/۶۲ mg/mL concentrations has destroyed EC, SA/BS and PA, respectively (p≤۰.۰۱). SLVAE had the most antibacterial activity on PA. In conclusion the obtained results indicated the antibacterial effect of SLVAE on EC, PA, SA, and BS. It seems that this plant can be used for the treatment of some bacterial infections as an antibiotic.کلیدواژه ها
Stachys lavandulifolia Vahl, aqueous extract, antibacterial propertyاطلاعات بیشتر در مورد COI
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