Extracellular Vesicles in Regenerative Medicine, a Brief Review
- سال انتشار: 1398
- محل انتشار: دوفصلنامه آزمایشگاه پزشکی مدرن، دوره: 2، شماره: 2
- کد COI اختصاصی: JR_MML-2-2_002
- زبان مقاله: انگلیسی
- تعداد مشاهده: 323
نویسندگان
Dept. of Stem Cells and Developmental Biology at Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
HPGC Research Group, Department of Medical Biotechnology, Pasteur Institute of Iran, Tehran, Iran
Dept. of Molecular Systems Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran
چکیده
Extracellular vesicles were initially known as cellular waste carriers, while recent studies demonstrate that extracellular vesicles play important biological roles in all aspects of life-from single cells to mammalians. Their pathophysiological roles in some diseases like cancer are being decoded. Extracellular vesicles are divided into some classes and there are different strategies to isolate them. Regenerative medicine is a collective term which comprised of different approaches to heal and repair damaged tissues and organs. A wide spectrum of options in regenerative medicine, makes this more dynamic field, which is appealing prospect for cell therapists and tissue engineers. EVs derived from mesenchymal stem/stromal cells and other probable sources are one of the options on the table to regenerate damaged tissues with lower risks, but their potential roles have not been fully elucidated. This cell-free based approach inspires cell therapist and tissue engineers in order to control immune reactions as well as regeneration at the same time.کلیدواژه ها
Extracellular vesicles, Exosomes, Regenerative Medicine, Cell Therapy, Tissue Engineeringاطلاعات بیشتر در مورد COI
COI مخفف عبارت CIVILICA Object Identifier به معنی شناسه سیویلیکا برای اسناد است. COI کدی است که مطابق محل انتشار، به مقالات کنفرانسها و ژورنالهای داخل کشور به هنگام نمایه سازی بر روی پایگاه استنادی سیویلیکا اختصاص می یابد.
کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.