Human Herpes virus-۸ in Kaposi sarcoma

سال انتشار: 1400
محل انتشار: اولین کنگره ملی رویکردهای نوآورانه در سیستم بیولوژی، داروسازی وصنایع غذایی
کد COI اختصاصی: SBPFST01_003
زبان مقاله: انگلیسی
تعداد مشاهده: 309

نویسندگان

Undergraduate student, Department of Microbiology Faculty of Advanced Science & Technology Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

Faezeh Ziaee

Undergraduate student, Department of Microbiology Faculty of Advanced Science & Technology Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

Rezvan Jahani

Undergraduate student, Department of Microbiology Faculty of Advanced Science & Technology Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

Shaghayeg Yazdani

Ph.D Assistant Professor of Virology Department of Microbiology Faculty of Advanced Science & Technology Tehran Medical Sciences, Islamic Azad University, Tehran, Iran

چکیده

Human herpesvirus ۸, also known as Kaposi's sarcoma virus (KSHV), is one of the few pathogens known to be directly carcinogenic, causing more than ۴۰,۰۰۰ cases of cancer and ۲۰,۰۰۰ deaths annually. Become all over the world.The KSHV virus has recently been discovered. It was first isolated from Kaposi sarcoma in ۱۹۹۴, hence its name. Apart from Kaposi's sarcoma, KSHV causes two lymphoproliferative disorders, primary lymphoma effusion, and Cestelman's multicenter disease.EPIDEMIOLOGY OF KSHV INFECTION Unlike other ubiquitous herpes viruses, the serum prevalence of KSHV is significantly lower and varies from region to region.Indigenous areas in Africa and the Middle East, where the serum prevalence of KSHV infection in the general population is between ۱۴% and ۸۶%, the highest serum prevalence is found in the so-called "Kaposi sarcoma belt" sub-Saharan Africa.The average prevalence of KSHV infection in southern Europe is estimated to be between ۱۰ and ۳۰%.In the United States and Northern Europe, the serum prevalence of KSHV infection in the general population is low, estimated at about ۶%.In these areas with low serum prevalence, the highest rates were recorded in HIV-positive men (MSM) (۳۰-۶۰%) and HIV-negative MSM (۲۰-۳۰%).

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