A Six-Month Survey of the Frequency of Extensively Drug-resistant Gram-Negative Bacteria by VITEK ۲ System in ۲۰۲۰
- سال انتشار: 1400
- محل انتشار: فصلنامه میکروب شناسی پزشکی ایران، دوره: 16، شماره: 2
- کد COI اختصاصی: JR_IJMM-16-2_005
- زبان مقاله: انگلیسی
- تعداد مشاهده: 175
نویسندگان
Department of Microbiology, Payvand Clinical and Specialty Laboratory, Tehran, Iran
Department of Microbiology, Payvand Clinical and Specialty Laboratory, Tehran, Iran
Department of Microbiology, Payvand Clinical and Specialty Laboratory, Tehran, Iran
Department of Microbiology, Payvand Clinical and Specialty Laboratory, Tehran, Iran
Head of Payvand Clinical and Specialty Laboratory, Tehran, Iran
Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences (SBMU), Tehran, Iran
چکیده
Background and Objective: Increasing of resistant bacteria is a major concern globally. The emergence of XDR gram-negative bacteria is a more serious problem due to treatment limitations. This study aimed to evaluate the frequency of extensively drug-resistant (XDR) gram-negative bacterial isolates in different clinical samples from Payvand Clinical and Specialty Laboratory, Tehran, Iran, for ۶ months by VITEK ۲ system. Materials and Methods: During March ۲۰۲۰-September ۲۰۲۰, different clinical samples were collected from patients referred to Payvand Clinical and Specialty Laboratory. Bacterial identification and antimicrobial susceptibility test (AST) were performed applying an automated VITEK ۲ system. The frequency of identified bacteria, their resistance to common antibiotics and also XDR bacteria were calculated and reported, respectively. Results: Overall, ۴۱۲۵ urine specimens, ۳۴ sputum samples, and ۱ tracheal aspirate tube were submitted to Payvand Laboratory during ۶ months. Of them, ۴۸۶ urine, ۳۲ sputum, and a tracheal aspirate tube samples were culture positive. Gram-negative isolated bacteria were included in this study. Based on AST, ۶۳.۳% of the isolated Klebsiella pneumoniae, ۱۰۰% of Pseudomonas aeruginosa, and all Acinetobacter baumannii isolates were susceptible to amikacin and colistin. Totally, ۳۱ XDR gram-negative bacteria, including: K. pneumonia (ssp. pneumonia (n=۲۰), and ozaenae (n=۲), Escherichia coli (n=۳), P. aeruginosa (n=۵), and A. baumannii (n=۱) were identified from ۱۸ urine samples, ۱۲ sputum specimens, and a tracheal aspirate tube. Conclusion: The rate of XDR bacteria was high in the investigated laboratory in this study. Therefore, accurate screening and antimicrobial stewardship is recommended in different medical centers of Iran.کلیدواژه ها
Automation, Drug resistance, Gram negative bacteria, antibiotics, اتوماسیون, مقاومت دارویی, باکتری های گرم منفی, آنتی بیوتیک هااطلاعات بیشتر در مورد COI
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کد COI به مفهوم کد ملی اسناد نمایه شده در سیویلیکا است و کدی یکتا و ثابت است و به همین دلیل همواره قابلیت استناد و پیگیری دارد.