Papillary Thyroid Carcinoma with Nodular Fasciitis-Like Stroma in a ۲۸-Year-Old Patient
- سال انتشار: 1401
- محل انتشار: فصلنامه آسیب شناسی ایران، دوره: 17، شماره: 2
- کد COI اختصاصی: JR_IJP-17-2_014
- زبان مقاله: انگلیسی
- تعداد مشاهده: 212
نویسندگان
Department of Otolaryngology-Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Otolaryngology-Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Department of Otolaryngology- Head and Neck Surgery, Otorhinolaryngology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
چکیده
AbstractPapillary thyroid carcinoma (PTC) is considered as a relatively common type of malignancy showing a wide morphologic spectrum. Different variants of this tumor have been reported. Among PTC variants, PTC with nodular fasciitis-like stroma (PTC‑FLS) is rare. This variant consists of stromal components rich in spindle cells and accounts for ۶۰-۸۰% of tumors. In addition, there are small foci of epithelial components in PTC‑FLS though its features are similar to conventional PTC. In this case study, we present a new case with PTC‑FLS. The case is a ۲۸-year-old female who was referred to the ENT clinic due to a painless mass on the anterior part of her neck. The mass showed a gradual increase in size over the ۶ months prior to her referral. Thyroid test results were normal. Ultrasound imaging demonstrated an ۸۴ × ۳۶ mm heterogeneous nodule in the right thyroid lobe without calcifications but increased vascularity. There were also some reactive lymph nodes in both sub-mandibular areas. An ultrasound-guided fine-needle aspiration (FNA) biopsy of the right thyroid lobe nodule revealed a benign thyroid adenomatoid nodule. Following right thyroid lobectomy, final pathologic studies confirmed a diagnosis of PTC with exuberant fibromatosis-like stroma. In the ۲۰-day post-surgery visit, the patient was found asymptomatic. Re-evaluation of the left thyroid lobe and follow-up were recommended. In this study, a diagnosis of a rare variant of PTC, i.e., PTC-FLS, was made through a combination of ultrasonography, fine needle aspiration cytology, and histological examination.کلیدواژه ها
Fibromatosis-like stroma, Neck mass, Papillary Thyroid Carcinomaاطلاعات بیشتر در مورد COI
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