Exploiting of Green Synthesized Doped Metal Oxide Nanosensor for Electrochemical Determination of Aspirin and Ibuprofen in Biological and Pharmaceutical Samples
- سال انتشار: 1400
- محل انتشار: دوفصلنامه ایرانی شیمی تجزیه، دوره: 8، شماره: 2
- کد COI اختصاصی: JR_IJAC-8-2_009
- زبان مقاله: انگلیسی
- تعداد مشاهده: 158
نویسندگان
Department of Chemistry, Payame Noor University, P.O. Box ۱۹۳۹۵-۴۶۹۷, Tehran, IRAN
Department of Animal Science Engineering, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, Iran
Department of Chemistry, Payame Noor University, P.O. Box ۱۹۳۹۵-۴۶۹۷, Tehran, IRAN
Department of Chemistry, Payame Noor University, P.O. Box ۱۹۳۹۵-۴۶۹۷, Tehran, IRAN
چکیده
The aim of the present study was to develop electrochemical sensors based on pencil graphite electrode modified with green-caped ZnO, CdO nano particles and potassium tetra chloroplatinate (II), for a simple and fast simultaneous microextraction and determination of Aspirin (ASA) and Ibuprofen (IBU). The nanoparticles were initially synthesized by the use of four vegetable extracts including garlic, onion, green onion and cabbage. The fabricated nanoparticles and platinum were then deposited on the surface of a pencil graphite electrode and was used as a working electrode in a three electrodes system. The Taguchi experimental design was employed for investigating the effects different parameters. For this purpose, a Taguchi L۱۶ orthogonal array (OA) design was applied and the results were confirmed by the ANOVA test. The electrochemical behavior of ASA and IBU at the modified electrodes, were studied. The calibration curves were linear in the range of ۵.۱۷to ۱۳۴.۰ µg.mL-۱ and ۳.۱۳ to ۲۳۱.۰ µg.mL-۱ for ASA and IBU respectively. The limits of detection for ASA and IBU was calculated to be ۰.۵۰ and ۰.۴۲ µg.mL-۱ respectively. The modified sensor showed good performance for simultaneous analysis of ASA and IBU in biological and pharmaceutical samples.کلیدواژه ها
Green-Caped ZnO/ CdO Nano Particles, voltammetry, Aspirin, Ibuprofen, platinumاطلاعات بیشتر در مورد COI
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